red wine and resveratrol research

dignan · Post by **dignan** » Sat Nov 05, 2005 8:30 am

Interesting stuff from an article about resveratrol and alzheimer's (see link)...

Marambaud and colleagues want to tweak resveratrol to make it a drug.

"We're going to take this natural compound as a scaffold and modify [it] chemically to make it more active and ... more stable," Marambaud says.

"It is known from previous studies that if you isolate, purify, or produce the compound directly and you inject it in mice, the compound is very rapidly degraded, mostly by the kidney system," he explains. "To use it as a drug like that is difficult."

Marambaud says his team has already developed a series of molecules that are 20 times more active than natural resveratrol in terms of reducing beta-amyloid protein.

Those molecules are already being tested on mice; tests will take six months to a year and will check for toxicity, Marambaud says.

He adds that resveratrol has been shown to have some "very interesting pharmacological effects" against herpes, some cancers, and possibly neurodegenerative diseases such as Huntington's.

http://www.webmd.com/content/Article/11 ... genumber=2

gibbledygook · Post by **gibbledygook** » Sun Nov 06, 2005 2:36 am

Great - I've been drinking red wine since I was 9 years old!! Still got MS though!

fightingms · Post by **fightingms** » Mon Nov 14, 2005 6:58 am

I have a glass of Merlot about once a month. Maybe it should be once a week. My Dr. told me it is the o and 1 wines like Merlot and Cabernet sp that the heart Dr.'s like people to drink.

Not the sweet wines, Which are 5 and 6 on the scale of wines, but the bitter ones that require a tast for them. I guess they have the most bioflavoiniods. This is the good thing in the wine for your heart and other things.