MS breakthrough: Vitamin D directly terminates production

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MS breakthrough: Vitamin D directly terminates production

Postby MSUK » Wed Aug 17, 2011 2:51 am

MS breakthrough: Vitamin D directly terminates production of disease-causing protein


Mechanism suggests a potential new path toward pharmaceutical treatment of MS, as well as therapies for other autoimmune diseases such as rheumatoid arthritis, type 1 diabetes, eczema and psoriasis.

For years scientists have noted an association between levels of vitamin D in a person’s body and the person’s ability to resist or minimize the effects of multiple sclerosis (MS) but didn’t understood the mechanism involved. Until now.

New breakthrough research by a collaborative team at UMDNJ-New Jersey Medical School and Stanford indicates that vitamin D directly terminates the production of a disease-causing protein.

As the investigators outline in their report, published in the September issue of Molecular and Cellular Biology (“1,25-Dihydroxyvitamin D3 ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A” )... Read More - ... ageid/1334
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Re: MS breakthrough: Vitamin D directly terminates productio

Postby HarryZ » Wed Aug 17, 2011 6:55 pm

If this discovery relies solely on what they found Vitamin D doing for the MS mouse, I wouldn't get too excited. Nothing that has worked in that poor mouse has translated into success with humans. But wouldn't it be nice if this was the first exception!

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