Axons and imaging

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

Axons and imaging

Postby dignan » Sun Nov 20, 2005 5:46 pm

I suppose if axonal degeneration is becoming a more important area of focus with MS research, it will be important to have the ability to monitor axonal preservation in clinical trials...

Optical coherence tomography: measuring in-vivo axonal survival and neuroprotection in multiple sclerosis and optic neuritis.

Curr Opin Ophthalmol. 2005 Dec;16(6):346-50.

Sergott RC.
Department of Ophthalmology, Neurology, and Neurosurgery, Thomas Jefferson University, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.

PURPOSE OF REVIEW: This review considers the latest developments in the use of optical coherence tomography in neuro-ophthalmology.

RECENT FINDINGS: Optical coherence tomography can accurately and reproducibly quantitate the micron thickness of the peripapillary retinal nerve fiber layer, as well as the thickness and volume of the macula. It is able to perform both cross-sectional and longitudinal studies in patients with multiple sclerosis and optic neuritis. It is able to measure and assess axonal preservation and protection when used in clinical trials.

SUMMARY: Specific guidelines when undertaking optical coherence tomography analyses for patients with multiple sclerosis and optic neuritis are needed to ensure uniformity among clinical trials; this development would be similar to the parameters devised when magnetic resonance imaging emerged as an important technology. ... query_hl=1
User avatar
Family Elder
Posts: 1608
Joined: Wed Aug 11, 2004 3:00 pm


Postby carolsue » Thu Aug 17, 2006 3:50 pm

picking this thread up because my neuro recently suggested optical coherence tomography to monitor my gray matter. has anyone else done this or had it suggested?

User avatar
Family Elder
Posts: 175
Joined: Sun Jul 25, 2004 3:00 pm
Location: Sunnydale, USA

Return to General Discussion


  • Related topics
    Last post

Who is online

Users browsing this forum: No registered users

Contact us | Terms of Service