Completion of planned enrollment in phase II MS trial

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Completion of planned enrollment in phase II MS trial

Postby MSUK » Mon Sep 19, 2011 8:01 am

Completion of planned enrollment in phase II MS trial of Trimesta™


Adeona Pharmaceuticals, Inc. announced today that the 150th patient has been enrolled in the randomized, double-blind, placebo-controlled, multi-center clinical trial of its Trimesta™ (oral estriol) drug candidate for relapsing-remitting multiple sclerosis (MS) in women, per the original protocol.

The Company also announced that Rhonda Voskuhl, M.D., Director, University of California, Los Angeles (UCLA) Multiple Sclerosis Program, UCLA Department of Neurology, and lead Principal Investigator of this Phase II clinical trial, has funding available to continue enrollment at all 15 centers, therefore, increasing the power of the trial. It is anticipated that the remaining grant funding will allow for the enrollment of an additional 10-20 patients.... Read More - ... ageid/1878
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Re: Completion of planned enrollment in phase II MS trial

Postby euphoniaa » Mon Sep 19, 2011 8:45 am

I've been pretty excited about the testing of estriol for MS, but, of course, this is yet another trial where the enrollees will be getting Copaxone along with either Trimesta or placebo. It's rare these days for them to test any new med alone and take the chance that the placebo patients will be left with no CRABs whatsoever. To me, that just confounds the results. And pisses me off. :smile:

The 150-patient, randomized, double-blind, placebo-controlled clinical trial of Trimesta is currently underway at 15 centers in the United States. Investigators are administering either Trimesta or matching placebo along with glatimer acetate (Copaxone®), an FDA-approved therapy for MS, to women between the ages of 18-50 who have been recently diagnosed with relapsing-remitting MS. With 127 out of 150 patients enrolled in the clinical trial by March 1, 2011, the Company anticipates full enrollment by the second half of 2011.
Dx'd with MS & HNPP (hereditary peripheral neuropathy) 7/03 but must have had MS for 30 yrs before that. I've never taken meds for MS except 1 yr experiment on LDN. (I found diet, exercise, sleep, humor, music help me the most.)
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Re: Completion of planned enrollment in phase II MS trial

Postby CureOrBust » Tue Sep 20, 2011 5:54 am

They should start using the oral therapies over the crabs, especially since they are testing a new oral treatment. I know one of the reasons I (if I was female in this case :wink: ) would join this trial would be because I disliked the injectibles. Are they listening?
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