This Is MS Multiple Sclerosis Community: Knowledge & Support

Hi All

Does anyone have chronic high white blood cell counts?

Mine have been coming back high with every blood test (monthly) for the last 2 years (and before).

They are sometimes severe, sometimes just high - but never anywhere near normal!

They are not the type that raises with infection - it's the inflammation ones but the test came back clear for Rheumatoid Arthritis

Just wondering if anyone else has this symptom? x

Hi Kizzydane,

What do you mean by " the inflamation kind"? Could you be more specific?

Donna

Hi Donna

Thank you for responding
I don't know which ones are chronically high - they did tell me but I just can't for the life of me remember the name!
I know the normal range is around 5 and mine have been coming back at around 22 with every blood test for the last 2 years. The doctor said it wasn't the ones that are high with infection but the ones that indicate some sort of inflammation.
I'll ask again next time I see the doctor x

WBC above 10,000 is not normal, it's a bone marrow disorder. Platelets may also be low around 80,000 or lower, (normal is 140,000 to 415,000) low Platelets will cause internal bleeding and bleeding from the mouth, nose, ears, eyes, rectum also pinhole bleeds on the arms and other parts of the body at various times this will occur around the 20,000 to 40,000 Platelet Count, and the Red Blood Count may also be low, this codition is called a Myeloproliferative Disorder; early onset Lukemia, sorry to say there is no treatment for this disorder at this time. Anyone with a high WBC needs to see a Hematologist which, is an Oncologist, the study of cancer. Do not delay get to a Hematologist or go directly to the ER if you feel dizzy, have a fever are sweating or have the chills, flu like conditions, you pass out, suffering from severe fatigue you also may have Pneumonia I was hospitalized for these conditions, you may be bleeding from the eyes, ears, mouth, rectum, or blood in your urine, again I was hospitalized for these conditions, if you have 2 or more of these conditions and have been tested with a high WBC go to the ER ASP!!! There are also Blast Cells that may show up in the Bone Marrow, this is fatal all the time. Eat red meat every day, take Green Tea Extract 12 tabs @400 mgs per day and take fish oll, also vitamin D3 4,000 mgs per day (order from Amazon.com) For the Flu like conditions I take NyQuil it helps, I am taking it now . I was diagnosed with this disorder on 8/12/2011 through the present, I have been in the hospital 6 times average 2 week stays, I am lucky to be alive. God bless you. This is very bad very bad condition, I hate it. It keeps coming back, sometimes I can't get out of bed, and my WBC Count keeps going higher, at 100,000 it's over, or when the Blast Cells come out around 100,000 and up, This is what 9 doctors have told me. This is a very rare condition. Use Google and type in High WBC followed by your numbers, Not much is known about this disorder, even doctors have very little information on this subject, however some Oncologists are very well versed on this disorder, but not many. You are all the blessed . I just don't know what else to say here. Man, Woman, Birth, Death, Infinity.

Copy and past;
http://www.cancer.gov/cancertopics/pdq/ ... ient/page4


wikipedia.org/wiki/Myeloproliferative_diseasewish

hi and welcome, KD

here's what good old wikipedia has to say about the kind of wbcs involved in chronic inflammatory processes
http://en.wikipedia.org/wiki/Inflammation

Chronic
Causative agent - Persistent acute inflammation due to non-degradable pathogens,viral infection, persistent foreign bodies, or autoimmune reactions
Major cells involved - Mononuclear cells (monocytes, macrophages, lymphocytes, plasma cells), fibroblasts

any of those sound familiar? monocytes look particularly relevant to multiple sclerosis..:

Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis
http://brain.oxfordjournals.org/content ... 2738.short
"...monocytes are prominent contributors of the neuroinflammation in multiple sclerosis"

i am starting to wish i had something different to say but once again, zinc rears its head.. found this interesting study (rats, but still)

Zinc-Deficiency Induced Changes in the Distribution of Rat White Blood Cells
https://www.jstage.jst.go.jp/article/jn ... 2/_article
"Zinc is known to play an important role for immune-functions. However, the effects of zinc-deficiency on the immune response system from the point of view of the distribution changes of the number of total white blood cells (WBCs) are still primarily unknown. Therefore, the effects of zinc-deficiency on the number of total WBCs, neutrophil, eosinophil, basophil, monocyte and lymphocytes (T lymphocyte, B lymphocyte and NK cell) were studied in rats. The weaned male rats were randomly divided into the zinc deficient diet (ZDD: 0.7 mg zinc/kg diet) group and the control diet (CON: 34.8 mg zinc/kg diet) group, and were pair-fed for 4 wk. The number of lymphocyte subsets, visceral organ weights, serum zinc, corticosterone and IL-6 concentrations were also determined. Zinc-deficiency increased duration-dependently the number of total white blood cells, granulocytes (neutrophil, eosinophil and basophil) and monocytes in 2-4 wk without changing the number of lymphocytes, T lymphocytes, B lymphocytes or NK cells. The relative weights of thymus and adrenals were 0.63 times (p<0.01) lower and 1.60 times (p<0.001) higher in ZDD group than in CON group, respectively. Zinc-deficiency increased serum corticosterone concentration to 1.48 times (p<0.05) without changing serum IL-6 concentration, as compared with those of CON group. From these results, zinc-deficiency increases markedly the number of granulocytes and monocytes without changing the number of lymphocytes, T lymphocytes, B lymphocytes or NK cells. These results also suggest that zinc-deficiency induces stress responses and the responses may have in part participated in increased actions of the number of granulocytes and monocytes during zinc-deficiency, and induce thymus atrophy and adrenal hypertrophy."

...as for condition of the thymus and adrenals in zinc deficiency too, interesting..

anyway if you've never had a zinc test it could be worth looking into. ms patients usually sit at the bottom of the normal range, healthy controls at the top end of the range. i have more detailed info posted in the 'signature' links below (eg test to request, what results to go for and why etc)

_________________
my approach: no meds so far - just balanced whole foods (partial 'paleo', much less outright elimination), science, supplements, & bloodwork
my regimen - www.thisisms.com/ftopict-2489.html
www.whfoods.com, www.nutritiondata.com