Cannabis capsules failed to slow the progression of multiple sclerosis in a large British study, dealing a blow to hopes that it could provide long-term benefits.
Despite promising signs in earlier, shorter studies, researchers found patients who took capsules containing tetrahydrocannabinol (THC), a key active ingredient in cannabis, fared no better than those given a placebo.
The finding is a disappointment for researchers who thought cannabis might provide a viable therapy in the disease's secondary progressive stage, when patients have few treatment options.
Multiple sclerosis (MS) patients were assessed in the trial known as CUPID (cannabinoid use in progressive inflammatory brain disease) on both a disability scale administered by neurologists and another based on their own reporting.
"Overall the study found no evidence to support an effect of THC on MS progression in either of the main outcomes," write researchers led by John Zajicek of the Peninsula College of Medicine and Dentistry, Plymouth University.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1815