can M,S cause hypertension/respritory problems???

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can M,S cause hypertension/respritory problems???

Postby melsy » Wed Oct 24, 2012 2:21 am

Hi all,
Iv posted recently regarding possible M.S, I am undiagnosed/treated.

I have just found out I am hypertensive and have been prescribed lisprionil 5mg blood pressure tabs. However, iv had attacks/episodes since taking my tabs and my blood pressure sores dangerously high after these episode and then comes back down, it appears from the cardiologist report, my heart etc is all fine, kidneys and adrenal glands and kidney scans, so it looks like the underlying condition I have, has now caused hypertension as another additional symptom (like all ready dont have enough)!
Vascular conditions I think were looked at before at the onset of the first chronic attack but no indication as yet.

Can M.S cause respritory problems and hypertension??? I am now thinking along the lines of neurosarcoidosis or something similar. I would of thought this would of been picked up on the 2 MRI'S I had???? any thoughts??

many thanks
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Re: can M,S cause hypertension/respritory problems???

Postby jimmylegs » Wed Oct 24, 2012 6:19 am

any of this sound possibly relevant?

Magnesium and Vascular Changes in Hypertension (2012)
http://www.ncbi.nlm.nih.gov/pubmed/22518291
Many factors have been implicated in the pathogenesis of hypertension, including changes in intracellular concentrations of calcium, sodium, potassium, and magnesium. There is a significant inverse correlation between serum magnesium and incidence of cardiovascular diseases. Magnesium is a mineral with important functions in the body such as antiarrhythmic effect, actions in vascular tone, contractility, glucose metabolism, and insulin homeostasis. In addition, lower concentrations of magnesium are associated with oxidative stress, proinflammatory state, endothelial dysfunction, platelet aggregation, insulin resistance, and hyperglycemia. The conflicting results of studies evaluating the effects of magnesium supplements on blood pressure and other cardiovascular outcomes indicate that the action of magnesium in the vascular system is present but not yet established. Therefore, this mineral supplementation is not indicated as part of antihypertensive treatment, and further studies are needed to better clarify the role of magnesium in the prevention and treatment of cardiovascular diseases.

Blood pressure and serum potassium levels in hypertensive patients receiving or not receiving antihypertensive treatment. (2007)
http://www.ncbi.nlm.nih.gov/pubmed/18058481
RESULTS: After adjusting for age, gender, and body mass index, significant negative correlations were found between serum potassium levels and systolic BP (R = -0.093, p = 0.007), diastolic BP (R = -0.078, p = 0.03), mean BP (R = -0.122, p = 0.002), and pulse pressure (R = -0.071, p = 0.044). The levels of potassium were found to be significantly lower among patients receiving diuretics than those receiving one of the other four drug categories of antihypertensive (p < 0.05 for beta-blockers, ACE inhibitors, and CCBs; p < 0.001 for ARBs). In addition, hypokalemia was found to be significantly more prevalent in the group using diuretics than the other groups.

CONCLUSIONS: The observed reverse relation between serum potassium and BP supports a close pathophysiological connection between serum potassium and essential hypertension. Moreover, diuretic therapy is a significant cause of hypokalemia and requires systematic monitoring.

i have had to deal with shortness of breath, inability to complete a proper deep breath, among other things.. issues resolved after magnesium tested in bottom end of normal range and i optimized serum levels to above 0.90 mmol/L.
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Re: can M,S cause hypertension/respritory problems???

Postby melsy » Wed Oct 24, 2012 8:35 am

Hi, funny you should mention potassium and sodium levels, I had this blood test done very recently - result was elevated potassium 5.8 and sodium 5.7, however this test was repeated the following day and came back normal, it was suggested that the first blood taken was contaminated. My kidney filteration was normal and my test on adrenal glands. I am due for another potassium etc blood test this week so I will see what the levels are this time. They cant find out whats causing the hypertension not alone the neurological symptoms. MRI''s still "essentially normal" regardless of the high signal intensity in both the front lobes...so I am at a total loss right now. Now it appears I have two fused vertebrate bones in neck (congenital) and no one will answer my question as to whether or not this is pushing on the 3 main arteriies to my brain??? this is clear on the mri but neuro has not mentioned it at all, so i am assuming again this is not the cause of my problems. urghhhhhhhhhhhhhh
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Re: can M,S cause hypertension/respritory problems???

Postby dignan » Wed Oct 24, 2012 1:41 pm

I'm no expert, but could this be another possibility?

http://drgabormate.com/why-they-call-it-blood-pressure/
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Re: can M,S cause hypertension/respritory problems???

Postby lyndacarol » Wed Oct 24, 2012 6:07 pm

Ask your physician for a "fasting blood insulin test." The optimum results should be 3 UU/ML or lower your.

Excess insulin has been linked to hypertension, as well as heart disease, high cholesterol, diabetes, and obesity. Investigate metabolic syndrome (a.k.a. Syndrome X) and discuss the possibility with your physician.
My hypothesis: excess insulin (hyperinsulinemia) plays a major role in MS, as developed in my initial post: http://www.thisisms.com/forum/general-discussion-f1/topic1878.html "Insulin – Could This Be the Key?"
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Re: can M,S cause hypertension/respritory problems???

Postby dania » Sat Dec 01, 2012 7:15 am

My blood pressure before I became symptomatic was normal 110/70 to 12/80. As my condition has worsened so has my blood pressure. I am now taking Lisinopril as I read it can help with MS symptoms. It does help me.
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