cheerleader wrote:Yes, Harry--it is part of CCSVI.
Studying CIS is very helpful in learning about how MS progresses. We've had several papers come out in the last couple of years, looking at the changes that occur to normal appearing white matter and gray matter BEFORE there is demylination and lesions. And the very first changes noted in the CIS brain, when compared to normals are:
1. Slowed blood flow, also known as hypoperfusion
2. Iron deposition into brain tissue.
The interesting fact is that these processes happen (in varying stages) in all neurodegenerative diseases. As Dr. Peter Stys has written in "Will the Real Multiple Sclerosis Please Stand Up", http://www.nature.com/nrn/journal/v13/n ... n3275.html it may due to the age of the patient at the onset of disease process which determines whether the patient develops MS, Parkinson's or Alzheimer's, since t cell activation in cytodegeneration happens in younger people, when the immune system is more active.
There will be a review of this science posted on CCSVI Alliance soon. The researchers at the International Society of Neurovascular Disease are modeling and studying how CCSVI could be involved in neurodegenerative disease. We're learning more,
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