This Is MS Multiple Sclerosis Community: Knowledge & Support

ScienceDaily (Nov. 27, 2012) — High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.

The conclusion is:
"In the mice, blocking fibrinogen's blood clotting activity prevented microglial activation and nerve damage.
Current drugs target primarily downstream events. This interaction could be an upstream target that suppresses immunity and neurodegeneration," said Dr. Akassoglou.

So, I looked at what natural supplements block fibrinogens blood clotting activity (I am not on any type of blood thinning mediciation).

*Nattokinase: a soy-derived dietary supplement and “fibinolytic” (clot-dissolving) enzyme, dissolves away excess fibrin deposits.
*Curcumin (a component of the herb turmeric)
*Serrapeptase: (serrapeptidase, Serratia peptidase), a proteolytic (protein-digesting) enzyme, is an anti-inflammatory nutritional medicine that dissolves plaque, and removes both fibrin and fibrinogen by digesting them. Serrapeptase also selectively removes many other proteins that impede healing and optimum health.
*Bromelain: This proteolytic (protein-digesting) enzyme derived from pineapple stems is one of the most effective fibrinogen-lowering agents. Bromelain (Ananas comosus) activates plasmin, our bodies’ own enzyme for lowering fibrinogen levels. Activated plasmin digests both fibrinogen and fibrin.
*Green tea and Flaxseed

Anyone else tried any of these added supplements? Benefits? Flax seed, curcumin and green tea I knew about. And even bromelain I have taken off and on through the years to aid in digestion. But, think I am going to start taking the bromelain again.
Full article:
http://www.sciencedaily.com/releases/20 ... 154215.htm

Hi Really--
we've been discussing this paper from Gladstone Labs here:
general-discussion-f1/topic21247.html
and on the CCSVI forum.

I created the Endothelial Health program for my husband back in 2008, to address his issues of hypercoagulation, inflammation and high SED rate. He takes papain and bromelain, both proteolytic enzymes, as well as quercetin, curcumin and EGCG. He took nattokinase for several months, until his blood panels looked normal. It's helped him....hope it can be useful to you, too!
http://www.ccsvi.org/index.php/helping- ... ial-health
take care,
cheer

_________________
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
dual stents placed 5/09
CCSVI in MS

Thanks!