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Good find! The really neat thing about this is we might be able to see what happens in MS with increased klotho when the Lisinopril study results are published. ACE inhibitors reduce Ang II. A reduction in Ang II is associated with an increase in klotho. So, good results from the study might just be partially attributable to upregulation of klotho. I do worry that the Lisinopril study results will be tainted by aldosterone breakthrough.
It seems like "they" are moving really fast with new discoveries about the impact of hormones outside of their traditionally known domains. Maybe it won't be too long before we have some answers.
Edited to rephrase. I don't recommend posting while chatting on the phone.
Last edited by Anonymoose on Fri Feb 08, 2013 4:21 pm, edited 1 time in total.
Hi Leonard, I was poking around Metformin trying to decide if it would be a better option than Clonidine. I stumbled across a page that warned of the dangers of B12 deficiency with metformin. http://www.metforminsideeffects.co/ I just thought I'd share in case that is what is holding back regaining sensation (I think I read that in the other thread). After reading a bit of your thread, I'm pretty sure you already know about that risk. Clonidine's not perfect either...can cause CQ10 deficiency.