This Is MS Multiple Sclerosis Community: Knowledge & Support

Hi. I've noticed that my symptoms--particularly the MS fatigue, leg weakness and dizziness-- tend to be much more pronounced in the early part of the day on into the afternoon. Come evening, it's often as if a fog is lifting and the symptoms lessen considerably. I find myself staying up, often as late as 3 or 4 o'clock in the morning, because I can function much better than during "normal" daylight hours.

Has anyone else experienced this "nocturnal lift" ?

Any ideas what the physiology is behind this? Wondered if it could have to do with cortisol levels?

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i have always been a night owl for the same reasons you state. even now, i can be dead tired all day and a lump on the couch for hours all evening but around 9 pm i seem to get a second wind. most of the time its frustrating because i should be asleep by 10 and even if i barely made it through work and was too tired to eat dinner suddenly i will be too awake for sleep. i start work at 7am and i still can't seem to get my natural clock on this schedule. i love the quiet middle of the night hours though

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Dx: 9/8/11 RRMS
Gluten and dairy free diet
copaxone x3: let's hope the third time is the charm!
http://mylaceybrain.wordpress.com

It's common in MS; some research points towards decreased endogenous melatonin production.

Hi gandy! just wonder, have u on drugs when u have that "nocturnal lift"?

I sure have a more energy level up until night when i used steroid. I maybe had insomnia because of steroid. And when i'm not on drugs, i found myself having a difficulty in sleeping at night too, but the reason is because my body doesn't feel good (having tingling, numbness all over my body) and i awake because i have to pee several times (one or two times) at night and i found it's difficult to sleep again after that.

Dear CuriousRobot,

Could u explain more about the relationship between "decreased endogenous melatonin production" and MS symptoms (or in this case "nocturnal lift") ?

Thank u very much for your explanation.

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Warm regards,
Linda

|For the joy of the Lord is your strength | A cheerful heart is good medicine, but a crushed spirit dries up the bones| God always leads us to where we need to be, not where we want to be|