BCG vaccine research in MS

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lyndacarol
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BCG vaccine research in MS

Post by lyndacarol »

Dr. Denise Faustman, Harvard researcher who is working on a type I diabetes treatment and who is Director of the Immunobiology Laboratory in Boston, has found that the BCG (Bacillus Calmette-Guérin) vaccine restores insulin production in the pancreas.

According to Dr. Faustman: Bacillus Calmette-Guérin (BCG) has an impeccable safety profile in humans. In fact, it has been labeled by some medical experts as the "safest vaccine" ever developed. BCG has been used for over 80 years worldwide as a vaccine for tuberculosis (TB) and is also used for the treatment of bladder cancer at high doses. In many countries, receiving BCG to prevent TB is mandatory.

In the update on her work which I received two days ago, I found the following, which concerns MS:
BCG Trials in Multiple Sclerosis Moving Forward in Italy
Our colleagues in Italy are moving forward with a Phase III trial testing BCG in patients with multiple sclerosis (MS). Led by Dr. Giovani Ristori at Sapienza University in Rome and supported by the Multiple Sclerosis Society of Europe, the trials will look at the clinical effect of BCG vaccinations in patients with early signs of MS. This is a follow-up to their Phase II study, which showed that even a single dose of BCG stopped multiple sclerosis progression in over half of patient compared to placebo.
Based on my knowledge of ONE case, I am not a believer in the success of BCG with MS.

I know of a woman with severe MS, who received multiple BCG vaccinations as a child growing up in Ireland (where it is part of required school vaccinations) when she moved and changed schools repeatedly.
Last edited by lyndacarol on Mon Nov 07, 2016 2:54 pm, edited 1 time in total.
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Scott1
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Re: BCG vaccine research in MS

Post by Scott1 »

Hi,

Can you post a link to both studies? BCG was compulsory for decades in Australia when I was a child but hasn't been for some time. They decided to stop because no one got TB.( a bit of a logic loop there)

I doubt it has any impact on MS but it would be interesting to see how they developed their arguments.

Regards,
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1eye
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Re: BCG vaccine research in MS

Post by 1eye »

Something which
restores insulin production in the pancreas
would be welcome to most diabetes sufferers. I assume there are many qualifications to this rather far-reaching claim. I haven't seen it on any front pages yet.
BCG vaccinations in patients with early signs of a mess.
should probably read "early signs of MS". :smile:
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lyndacarol
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Re: BCG vaccine research in MS

Post by lyndacarol »

Scott1 wrote:Can you post a link to both studies? BCG was compulsory for decades in Australia when I was a child but hasn't been for some time. They decided to stop because no one got TB.( a bit of a logic loop there)

I doubt it has any impact on MS but it would be interesting to see how they developed their arguments.
The information from Dr. Faustman includes a link to a one-page site, where other links are offered in the upper right-hand corner (I have not explored these links, where you may find the details you seek.).

http://www.faustmanlab.org/

I have no link for the BCG-MS research being done in Italy.
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