High dose Vitamin D3 has immunomodulatory effects in MS

[frodo]

This article reports a meta-study. 9 studies were compared, including 1022 participants. 630 of them were randomized to vitamin D3 supplementation in high dose, 171 in low-dose and 221 receiving placebo.

The effect of High Dose of Vitamin D3 on the Prognosis of Patients with Multiple Sclerosis
http://imed.pub/ojs/index.php/iam/article/view/2015

Conclusion.

There is evidence that high dose of Vitamin D3 provide immunomodulatory effects in patients with Multiple Sclerosis, showing improvement in the patients' prognosis.

[ElliotB]

The conclusion of the study is favorable but not specific:

"Conclusion. There is evidence that high dose of Vitamin D3 provide immunomodulatory effects in patients with Multiple Sclerosis, showing improvement in the patients' prognosis."

They unfortunately do not say what the improvements are.