Trigeminal neuralgia

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Trigeminal neuralgia

Postby koneall » Fri Sep 22, 2017 11:23 am

Is numbness a sign of MS? I read that pain in that area is a sign but for me it's numbness as if I've just been to the dentist. The numbness affects the lateral side of the mouth and upper teeth, places innervated by the trigeminal nerve.

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Re: Trigeminal neuralgia

Postby jimmylegs » Fri Sep 22, 2017 1:12 pm

hi :)

it's not a make or break diagnostic feature. depends what else is going on. there's a very long (~80) list of things to go through before arriving at an ms dx.

nothing to do with ms, but interesting:
The Study of Calcium, Phosphonium, Magnesium, and Ferrum Concentration in Serum of Patients With Primary Trigeminal Neuralgia
http://journals.lww.com/jcraniofacialsu ... nd.96.aspx
"In primary TN patients, the concentration of Ca, P, Mg in serum is lower than the control group obviously (P <0.05), but the concentration of Fe in serum is higher than the control group obviously (P <0.05)."

i have some problems with this article (eg am not used to seeing the word 'obviously' used where i would expect 'significantly', and never mind the rest of the sentence structure). i don't have full text access so can't take a closer look, but there are some take-away messages that could be useful follow up items anyway.

specifically, do you have bloodwork results for serum calcium, phosphorus, magnesium and ferritin?
(please don't say 'all normal' - am asking about actual numeric results, with units, whether low- mid- or high-normal)
odd sx? no dx? check w/ dietitian
DRI=MINIMUM eg bit.ly/1vgQclQ
99% don't meet these. meds/lifestyle can affect levels
status can be low in ms & other cond'ns
'but my results are normal'. typical panels don't test all
deficits occur in 'normal' range
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Re: Trigeminal neuralgia

Postby NHE » Sat Sep 23, 2017 1:09 am

jimmylegs wrote:i have some problems with this article (eg am not used to seeing the word 'obviously' used where i would expect 'significantly', and never mind the rest of the sentence structure). i don't have full text access so can't take a closer look, but there are some take-away messages that could be useful follow up items anyway.

Consider it lost in translation. The authors are Chinese.

    "Department of Neurosurgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."
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Re: Trigeminal neuralgia

Postby jimmylegs » Sat Sep 23, 2017 6:05 am

哦,我知道。我已经标明了CFL ELL学生的工作。他们的英文写作比我的中文写作更好,除了使用谷歌翻译的人。我可以做同样的事情!
odd sx? no dx? check w/ dietitian
DRI=MINIMUM eg bit.ly/1vgQclQ
99% don't meet these. meds/lifestyle can affect levels
status can be low in ms & other cond'ns
'but my results are normal'. typical panels don't test all
deficits occur in 'normal' range
User avatar
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Posts: 11114
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Re: Trigeminal neuralgia

Postby THX1138 » Sun Feb 18, 2018 10:39 pm

Effect of coenzyme Q10 on mitochondrial respiratory proteins in trigeminal neuralgia. https://www.ncbi.nlm.nih.gov/pubmed/29424256

consumerlab.com wrote that 100mg coenzyme Q10 taken 3 times a day for 2 months along with standard medication significantly reduced the pain of trigeminal neuralgia. They cited the above stud
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