FDA Requests Boxed Warning for Contrast Agents

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FDA Requests Boxed Warning for Contrast Agents

Postby flipflopper » Sat May 26, 2007 9:46 pm

This article is relevant to all of us. It's something to read before your next MRI done with a gadolinium-based contrast agent.


http://www.fda.gov/bbs/topics/NEWS/2007/NEW01638.html
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Postby Lyon » Sun May 27, 2007 9:56 am

Thanks flipflopper,
Hopefully the FDA will continue to follow up on this and develop more information
Reports have identified the development of NSF following single and multiple administrations of the gadolinium-based contrast agents. The reports have not always identified a specific agent. Omniscan was the most commonly reported agent, when a specific agent was identified, followed by Magnevist and OptiMARK.
it would be nice to know if there is something inherently more dangerous about Omniscan, or the situation involves it being the most used agent.
There have been no reports of NSF among patients with normal kidney function or those with mild-to-moderate kidney insufficiency.
And you always have to wonder about the negative effects over time for someone with good kidneys. Although problems showed up first for people with weaker kidneys, it's foolish to think that good kidneys are unaffected.

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