I think with some of the treatments in Phase III (see Dignan's list), the "story" of someone with MS in ten years will be VERY different to the past ten years.Rinn wrote:What I really want to know is - for those of you who were diagnosed in their 20's (I'm 26)...how has it been since? for instance, I meet a lot of people who are in their 40's and are using some type of mobility assistance. But when they were in their 20's were they ok?
Just wondering what my future has in store for me. And your stories would be greatly appreciated.
Recent works suggest that the progressive phase in multiple sclerosis could be an age-dependent, degenerative process, independent of previous relapses, and that the initial course of the disease does not substantially influence age at disability milestones.
SUMMARY: Overall course and prognosis in multiple sclerosis is most likely to be related to age and the occurrence of the progressive phase of the disease, rather than to relapses or other clinical parameters. Individual prognosis remains hazardous.
For the 1844 patients, median ages at time of assignment of irreversible disability were
44.3 years.....for a score of DSS 4, (note--per abstract limited walking without aid)
54.7 years....for DSS 6
63.1 years...for DSS 7 (note--per abstract wheel chair bound).
These results were essentially similar whether the initial course of multiple sclerosis was exacerbating-remitting or progressive, and whatever the initial symptomatology. Females reached disability milestones at an older age than males.
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