I don't really understand most of this paper, but the combination of epigenetics and neural stem cells was too interesting to ignore.
Epigenetics and neural stem cell commitment
Hai-Liang TANG, Jian-Hong ZHU
Department of Neurosurgery, Fudan University, Huashan Hospital, Shanghai 200040, China
National Key Laboratory for Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refer to the study of mitotical/meiotical heritage changes in gene function that cannot be explained by changes in the DNA sequence. Major epigenetic mechanisms include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, and non-coding RNA. In this review, we focus on the new insights into the epigenetic mechanism for neural stem cells fate.
To read the entire paper: http://www.neurosci.cn/article/v23/241.pdf