I’m not taking the “patented” Trimesta but I have been on 8mg of compounded estriol (+ 500 mg of bioidentical progesterone) for about 3 years now and I’d basically say so far so good. Of course I’m sure you know given the unpredictable nature of MS that I have no idea if the hormones are what’s contributing to the “so far so good”. I'm 61 and was diagnosed about 4 years ago. I'm also on Copaxone, Swank diet (more or less), exercise and do some supplements.
And, while I don’t know if you might be concerned about the potential risks of estrogen, I sense many women are, so here are links to two full articles with lots of information on that topic. The first article, HRT: a reappraisal of the risks and benefits
is pretty readable and there’s a great graph at the end.
Here’s the second article, A Comprehensive Review of the Safety and Efficacy of Bioidentical Hormones for the Management of Menopause and Related Health Risks
, also quite readable. (Estriol is a "bio-identical hormone".)
And, if you consider estriol, I personally think you might also want to consider having your hormone levels tested. There’s a possibility, among others, that you might be low in progesterone and it seems to have lots of neuroprotective and remyelinating potential. Here’s a recent abstract on that:
Progesterone: Therapeutic opportunities for neuroprotection and myelin repair
Now, I’m curious too, is anyone else taking estriol (Trimesta)?
Thanks for the patent info on Trimesta. There was another patent related to estrogen and neuroprotection in 1996. Here's the link
. Unfortunately, most of it is very scientific and not easy to read.
Take care all