Current Clinical Studies (US)

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Current Clinical Studies (US)

Postby Artifishual » Wed Jan 07, 2009 9:35 am

this is a list of current ms studies that are seeking volunteers.

Found 153 studies with search of: Open Studies | "Multiple Sclerosis" ... lerosis%22
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Postby mrhodes40 » Wed Jan 07, 2009 10:23 am

Thanks for posting this!

Wow the first one on that list is a study with mesenchymal stem cells and they are just giving the stem cells, no chemo

Intervention Details:
Biological: Autologous mesenchymal stem cell transplantation
A single IV infusion of up to 2 million cells per kg based on the MSC numbers achieved after culture expansion

Now that is the study I have been waiting to see the results of,
bad news is that it is not expected to complete until 2012 and it is so small with 24 pateints that it will only be considered preliminary. The results will necessarily be something like "This study shows that autologous MSC is reasonably well tolerated and safe in MS patients further studies are warranted...".

Good grief.... It'll be 2020 before this is available........assuming it helps people.

Meantime the Chinese Thailandese & Costa Rican clinics will continue to do this for profit, so we may hear more from that.

My belief is though that this will need to be done repeatedly, like very 6 months, just like the other approaches like campath tysabri etc. They know from other studies it modulates the immune system making it more tolerant and it also may allow some migration to the damaged area for some healing. Why on earth assume this will work in one magical infusion when MS is an ongoing disease? My guess is people will feel pretty good in the short term but with time will not be remarkably different if given only one infusion. :roll:
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Postby gainsbourg » Fri Jan 09, 2009 2:43 pm

I'm all for human studies. It beats cutting the heads off rats anyday!

Marie I have tried to reply to your message but the software just won't let me send

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Postby CureOrBust » Fri Jan 09, 2009 7:39 pm

mrhodes40 wrote:Meantime the Chinese Thailandese & Costa Rican clinics will continue to do this for profit, so we may hear more from that.
I saw a bit of an eye-opener the other day on TV about a chinese Dr & clinic. It was about something stem cell related (they appeared to be using growth factors or something from embryonic stem cells, or something, I missed the start of the program), for ALS. There was a British man being "followed" through treatment.

In the operation, they inject the substance (stem cells or growth factor or whatever) into a location deep inside the brain, using long syringes. The scary part was that it involved drilling two holes in the front of his skull, just above the hairline, about 10cm apart. The actual drilling looked to be performed with a cordless drill they had picked up from the local hardware. Seriously, no exageration! I would swear they were using one of these below (except a different colour, more of a green instead of grey), and it was being used "hand-held", not being directed by any robotic arm or something.
Nothing of medical importance, but I certainly would not be lining up for THIS particular clinic. I saw this last week, and was looking for an opening to post this :roll:

PS: It didn't help the man too much. He felt he could move one of his fingers a little more, but his treating neurologist back in the UK tried to make him understand that the change in movement was minimal, and could be simply a normal periodic adjustment in his condition.
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