i see i missed responding to some input here, sorry my bad
viper: ever had your zinc tested? or your PUFAs?
peek: in addition to being a critical nutrient for liver function, zinc also helps the adrenals battle cortisol.
catfreak: i have psoriasis too and some of it cleared up when i fixed the zinc issue. the only other time i have gotten rid of it is by basically being in the sun ALL THE TIME which i have not been able to do since high school.
it's a kidney thing to some extent and i have found it REALLY HARD to research (therefore i spend less time on it) so i'm still using a topical prescription of corticosteroid mixed with 1,25dihydroxyvitd3 (what good kidneys make on their own, stupid lazy kidneys - maternal grandpa died young from kidney cancer)
turtle: you just ask for a requisition for a zinc test. a plasma zinc level. the ontario health insurance plan simply calls it "zinc", but the lab i use offers both plasma and urine tests so wherever you are you may want to specify.
alternatively, you can try this home testing method: the Zinc Taste Test
http://www.msrc.co.uk/index.cfm?fuseact ... pageid=653
cheer: so is jeff's zinc low normal, mid, or near optimal? did the lab ever give you a specific number?
ran across another study, on livers both ratty and fatty, and thought i'd tack it on here:
J Nutr. 1994 Oct;124(10):1917-26.
Dietary fat influences the effect of zinc deficiency on liver lipids and fatty acids in rats force-fed equal quantities of diet.
Previous studies showed that zinc deficiency influences the fatty acid composition of rat tissues, but the influence of dietary fat on the effects of zinc deficiency was not considered at that time. The present study was therefore conducted to investigate the effect of zinc deficiency on lipid concentrations in the liver and on fatty acid composition of liver phospholipids in rats fed diets containing coconut oil or fish oil, using a bifactorial experimental design. To ensure an adequate food intake all rats were force-fed. The zinc-deficient rats fed the coconut oil diet developed fatty livers, whereas zinc-deficient animals fed the fish oil diet did not
. The zinc-deficient rats in both dietary fat groups had lower levels of linoleic acid, arachidonic acid and total (n-6) fatty acids in the liver phospholipids, especially in the phosphatidylcholine, but greater concentrations of (n-3) fatty acids compared with zinc-adequate controls. We conjecture that zinc deficiency influences incorporation of polyunsaturated fatty acids into phosphatidylcholine. The lower levels of arachidonic acid are replaced in the zinc-deficient animals fed a coconut oil diet by docosapentaenoic and docosahexaenoic acids and in the zinc-deficient animals fed a fish oil diet by eicosapentaenoic acid. The replacement of arachidonic acid by other fatty acids in the phospholipids is likely to have implications for prostaglandin synthesis
. The study shows that the type of dietary fat influences the effects of zinc deficiency on fatty acid composition and especially on lipid concentrations in the liver.
There are currently ten known prostaglandin receptors
on various cell types.
The diversity of receptors means that prostaglandins act on an array of cells and have a wide variety of effects:
-cause constriction or dilation in vascular smooth muscle cells
-cause aggregation or disaggregation of platelets
-sensitize spinal neurons to pain
-decrease intraocular pressure
-regulate inflammatory mediation
-regulate calcium movement
-control hormone regulation
-control cell growth