Iron compunds and ms

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Iron compunds and ms

Postby bromley » Sun Jan 23, 2005 10:16 am

Dear all,

The role of iron in cns degenerative diseases has been discussed before on this site. The attached BBC article should be of interest.

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Postby OddDuck » Sun Jan 23, 2005 7:49 pm

Yes, that is interesting, bromley!!

Funny you posted that! I just read something similar in the past couple of days. Free radicals and iron deposition. Oh! And there was a new theory connected with that somehow, whereby they believe the body is somehow mistaking certain glycolipids as "foreign" and launches an attack on the body, which is NOT foreign. (I don't know.........something like that.) And it all went back to the "free radicals" thing, too. (Sorry.......I know this probably isn't making much sense, but I read it all in passing, and was really trying to focus on something else, so I didn't exactly memorize it all. It started with Alzheimers, though, somehow, also, but led right into MS.) Shoot.........sometimes I start with one thing, and end up at a totally different end in my research and I sometimes skip or don't remember things I run across in between.

Anyway, it really makes a person want to load up on as many anti-oxidants as you can get your hands on, doesn't it!

And I STILL say green tea is a good one! :wink: I don't care WHAT the neuros think!

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Re: Iron compunds and ms

Postby NHE » Mon Jan 24, 2005 4:26 am

OddDuck wrote:And I STILL say green tea is a good one! Wink I don't care WHAT the neuros think!

Epigallocatechin gallate (or EGCG), one of the principle antioxidants found in green tea, is known to inhibit the transcription factor NF-kB which is responsible for the production of several proinflammatory cell signaling proteins. In spite of the generic "antioxidants boost the immune system" mantra that I've run across, I believe that inhibiting NF-kB should be a good thing for MS patients since it should lead to less overall inflammation in the body and that each antioxidant needs to be evaluated individually as to whether or not it might be helpful for MS.

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