Welcome to ThisIsMS, Anita (amoore282).
Since you are seeking "any advice," here is mine:
Your list of symptoms was very well done! Your symptoms are consistent with MANY diseases, including MS – which is a diagnosis of exclusion. The more likely causes of the symptoms must be ruled out first before the diagnosis of MS can be made. Your "numbness/tingling feet-legs/hands-arms" is called "peripheral neuropathy." The University of Chicago suggests investigating peripheral neuropathy by testing for the following:http://peripheralneuropathycenter.uchic ... #bloodtest
Blood tests are commonly employed to check for vitamin deficiencies, toxic elements and evidence of an abnormal immune response.
Depending on your individual situation, your doctor may request certain laboratory tests to identify potentially treatable causes for neuropathy. These include tests for:
Vitamin B12 and folate levels
Thyroid, liver and kidney functions
Oral glucose tolerance test
Antibodies to nerve components (e.g., anti-MAG antibody)
Antibodies related to celiac disease
Hepatitis C and B
And ask for your own copy of any test results. Please note that the first blood test the U of Chicago suggests is for vitamin B12. Since all your symptoms are consistent with a B12 deficiency, I agree with the U of Chicago that this is the place to start. BUT since you have been getting B12 shots over the last two years, blood test results for B12 would be skewed and unreliable. By the way, if these injections have been done in a doctor's office in the US, they are cyano
cobalamin (a.k.a. cyano B12, which is not handled by the body as well as methyl
B12 is). A trial of methyl
B12 injections (available from a compounding pharmacy) might be worthwhile. As you probably know, B12 is non-toxic, has no side effects, and is inexpensive. Even if you have adequate B12 in blood you can still be deficient in the cells (if you are lacking the proper transport molecule required to take the B12 from the blood to the cells). An additional blood test for this transporter molecule (called the HoloTc test) can indicate if this is the problem. Any person at any age can develop a B12 deficiency in the blood or in the tissues.
I urge you to read the book, Could It Be B12? An Epidemic of Misdiagnoses
by Sally M. Pacholok, RN, BSN, and Dr. Jeffrey J. Stuart, D.O. (This may be available at your library.):http://b12awareness.org/could-it-be-b12 ... diagnoses/
Take a deep breath, Anita. We are glad you found us.