Definitely. I had some surgery and Fentanyl IV was used, it didn't help me at all with the pain, and I was off LDN for about a week. I received a Morphine shot in the IV post surgery and it made little difference.
I am on LDN for 3 years now. I need more surgery (eye this time) so I stopped it for two weeks this time. I feel tired and know I need my LDN fix badly. It helps with pain and is uplifting for mood too.
Where there is a will, there is a way. "HOPE"
CCSVI Procedure December 2010