Taking a break from LDN

A board to discuss Low Dose Naltrexone (LDN) as a treatment for Multiple Sclerosis

Taking a break from LDN

Postby Arfie » Fri Jul 02, 2004 8:46 am

I have been taking LDN for almost 4 months without a break.

Can someone advise on the effects of stopping LDN for a short term.

There seems to be mixed opinions on dependancy and effect after continous usage. Has anyone got any thoughts on this?

Arfie 33 RRMS Aug03
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Postby Andy » Sat Jul 03, 2004 3:15 pm

Hi Arfie, I have been on LDN since Feb of this year and I personally (on advice from a doctor who himself has MS) take LDN for 2 weeks ON then 2 days OFF, this regime seems to suit me ok, I am on 3mg/day and no longer have pains in my feet and ankles nor do I have to get up through the night to use the loo. BRILLIANT !!!!
I have PPMS dx 1995

Hope you get good results too.

ps Hope this is helpful to you.
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LDN breaks.....

Postby JoyceF » Sat Jul 03, 2004 3:19 pm

Hi Arfie,
There seems to be two schools of thought on this particular topic. Dr. Bihari does not feel that there is a need for any such breaks from the daily use of LDN, whereas, Dr. Lawrence feels that there might be some sort of accommodation that might occur. He advocates taking a break about every 10 days or so I think (not sure about the schedule because I have never taken an intentional break, I have missed a dose once or twice and never noticed a difference on those days when I did). I have heard it said that there are those that take a break and those that don't so I spose it is entirely up to you. Good luck.
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Postby SammyJo » Mon Jul 12, 2004 9:36 am

I started Feb 02 also. After 2-3 months started having sleep disturbance, which was odd because one of the first effects I saw was that I slept like a rock, with no more twitching. Im on 4.5mg, and now I do the every 10th day off. Has kept sleep normal, and I don't notice any major downturn from the 1 day break.

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