Brain cannabinoid CB1 receptors blunted in cannabis users

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Brain cannabinoid CB1 receptors blunted in cannabis users

Postby MSUK » Thu Jun 09, 2011 10:55 pm


Chronic marijuana smokers show a decrease in cannabinoid CB1 receptor activity, which correlates with the number of years of cannabis smoking, but the deficits are reversed after just 4 weeks of abstinence, according to research presented here at the Society for Nuclear Medicine 2011 Annual Meeting.

Cannabinoid CB1 receptors influence brain functions, including pleasure, appetite, concentration, perception of time and memory, pain tolerance, and other psychological and physiological functions. Previous studies on rodents have shown a downregulation in CB1 receptors related to chronic cannabis exposure, followed by recovery during abstinence.... Read More - ... ageid/1815
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