all things vitamin D

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Postby jimmylegs » Thu Aug 13, 2009 1:01 pm

yes ken there's that pesky ascertainment bias to consider.
found this blurb on it (never heard of MS being an STI before, but you learn something new every day)

http://tiny.cc/oRLo2
Chapter VIII (Hawkes) in 'Treatment and management of multiple sclerosis' By Frank H. Columbus

There is evidence from twin surveys that females tend to be over-represented in volunteer-based studies. This has been termed the 'rule of two thirds' because of the 2:1 ratio of females to males. The implication for MS epidemiology is hard to predict but an apparent excess of females in volunteer-based studies may be due to ascertainment bias... data from mortality studies where ascertainment bias is low make it most likely that females do suffer more from MS but this potential source of bias should not be ignored. Many apparent clusters have been associated with entry of soldiers in wartme... troops would be accompanied by medical personnel who might increase the standard of health care in the resident population. This would have the potential to improve case ascertainment as well as health care all round. Despite all these reservations clusters may be biologically if not statistically significant and may contain aetiological clues if the right questions are asked or the correct test performed...
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Vit D Jimmy?

Postby Lyon » Sun Aug 16, 2009 7:02 am

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Postby jimmylegs » Sun Aug 16, 2009 7:09 am

that's funny lyon, did you post this because you saw the recent back and forth on d3 and Tregs? http://www.thisisms.com/ftopic-7868-15.html
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Postby Lyon » Sun Aug 16, 2009 7:13 am

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Postby jimmylegs » Sun Aug 16, 2009 7:23 am

sorry, didn't mean to imply a heated debate :?
i've been talking about d3 being the immune system's brakes pretty much since i joined TIMS, so i guess i don't follow the new stuff like i should. thanks for posting the link.
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Postby Lyon » Sun Aug 16, 2009 7:58 am

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Postby jimmylegs » Sun Aug 16, 2009 9:10 am

LOL!!! yes a true canadian, sorry and all lol
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Is anyone else taking super high Vitamin D doses?

Postby ElMarino » Thu Aug 20, 2009 7:15 am

I just wondered because, of all the do-it-yourself treatments that I've tried (Tryptophan, NAG, B12, I-can't-remember-what-else-over-the-years!) I actually have a very good feeling about this.

You see ever since I was a child I've had eczema. It used to be pretty bad but, with avoiding perfumed soap and detergent it's completrely under control. I've felt it was linked with my MS, during a relapse the eczema was likely to be worst and, besides, they are both auto immune reactions gone wrong, right? Anyway, since reading this article http://www.webmd.com/multiple-sclerosis ... s-relapses mid spring I have been taking 14,000 iU of vitamin D on days when it hasn't been sunny enough to spend 45 minutes on my balcony in the sun. It just so happens that a week ago, for the first time since I was five years old, my eczema has completely dissapeared. I've no idea if it will last but it does make me mildly optimistic.

So, has anybody else been on high vitamin D since the study was published?

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Postby jimmylegs » Thu Aug 20, 2009 8:32 am

hi E, if you go under regimens and read the Orthomolecular etc Mega D thread you can see what i have been doing since 2006 and high-dosing d3. hasn't cleared up all my skin probs yet, but mine are not eczema. it's pretty fun when you hit on something that makes a diff for you, isn't it!
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Postby notasperfectasyou » Thu Aug 20, 2009 8:50 am

Kim is taking D3 8000-9000/day. She got a script from her Neurologist for 50000 once a week, but our farm'acy only had D2 and we wanted D3. So he said it was ok to continue on the ones we get OTC. But, Kim has been on high dose D from even before that. There is a lot of stuff out there on it. Ken
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Postby Mamacita » Thu Aug 20, 2009 9:39 am

My husband only tests his D levels once or twice a year when he goes in to see one of his doctors. He takes 5000 IU/day, and he's usually at around 50ng/ml. That's about 125nanomoles/liter, I think. We're going to try to creep him up a little higher though.

--Mamacita
http://multiplesclerosisrecipes.blogspot.com/
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Postby jimmylegs » Thu Aug 20, 2009 11:06 am

you've got him right in the sweet spot by the sounds of things! but yea i try to go for 150 too.
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Postby MrsGeorge » Thu Aug 20, 2009 12:48 pm

I was but I sopped. I need to start it up again, especially because I have eczema. Thanks for pointing it out!
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Postby notasperfectasyou » Thu Aug 20, 2009 12:53 pm

I don't know if the bumps Kim's had on her face is Eczema, but when she started on ABX, it cleared up. Ken
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Postby Wonderfulworld » Thu Aug 20, 2009 12:59 pm

I am on 4000IU D3 a day.
Two things happened about 5 months after starting the regime.

I stopped having monthly migraines.
My dishydriotic eczema cleared up.

I recently had a flare up but it was mainly sensory symptoms and brain fog and seems to be clearing up without the "take to the bed for a month" routine that it normally takes, this time of year.
I have a good feeling about it too.
~~~~~~~~~~~~~~~
Concussus Resurgo
~~~~~~~~~~~~~~~
RR-MS dx 1998 and Coeliac dx 2003
~~~~~~~~~~~~~~~
Copaxone, Cymbalta. EPO, Fish Oils, Vitamin D3 2000 IU daily, Cal/Mag/Zinc, Multivitamin/mineral, Co-Enzyme Q10, Probiotics, Milk Thistle.
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