Lancet. 1995 Apr 8;345(8954):897-8.
Focal white-matter lesions in brain of patients with inflammatory bowel disease.
Geissler A, Andus T, Roth M, Kullmann F, Caesar I, Held P, Gross V, Feuerbach S, Scholmerich J. Department of Internal Medicine I, University of Regensburg, Germany.
Inflammatory bowel diseases are often associated with extra-intestinal manifestations, such as arthritis and iritis/uveitis. Using magnetic-resonance imaging we found hyperintense focal white-matter lesions in the brain in 20 of 48 (42%) patients with Crohn's disease, in 11 of 24 (46%) patients with ulcerative colitis, but in only 8 of 50 (16%) healthy age-matched controls (relative risk [95% CI] vs controls 2.6 [1.3-5.3] and 2.9 [1.3-6.2], respectively). These findings may represent another extra-intestinal manifestation of inflammatory bowel disease.
Last edited by beatms
on Mon May 28, 2007 11:33 am, edited 10 times in total.