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A board to discuss the Multiple Sclerosis modifying drug Avonex

Ughh horrible

i have been on avonex for 3 months now, after being taken off rebif. I honestly feel worse on the shots than i did when i wasnt on them. I have had more problems walking, talking, thinking, everything. Needless to say, today i decided to stop the shots, at least for a while. So many people have called me stupid for this decision. MS is hard enough to deal with. I dont need shots making ...
Read more : Ughh horrible | Views : 3280 | Replies : 4

Daughter in law with MS

I have a daughter in law with MS and her doctor prescribed Avonex. The next day she needed a cain to walk. I have been trying to get her to try Dr. Swanks diet but for some reason she would rather do the drugs. I am trying to understand why? Everything I have seen shows the drugs do not work. Does anyone have a study showing these drugs work? Is it just believing the doctor ...
Read more : Daughter in law with MS | Views : 2548 | Replies : 0

Side effects?

I've been on Avonex for 4 months. After shot, every Saturday I feel terrible, like a bus hit me. I don't have any strentgth to get up from my bed. And all Saturday I have big numbness in my right hand (like relapse). I can't to use this hand. I can't hold a pen.
But on Sunday I feel good and my right hand is good.
I don't know what thinking about my right ...
Read more : Side effects? | Views : 3404 | Replies : 10

Genetic sensitivity to interferon-beta

My father recently had a DNA profile done and one of the traits that came back was a significantly increased sensitivity to interferon beta.

"This study examined 199 patients from Spain with clinically diagnosed relapsing-remitting multiple sclerosis who had received interferon beta treatment for at least two years. The authors classified patients as “non-responders” if, over the two year period of interferon beta treatment, they had two or more disease relapses, or if their Expanded ...
Read more : Genetic sensitivity to interferon-beta | Views : 2373 | Replies : 1

Mixed results seen for immediate MS treatment


Multiple sclerosis patients had fewer relapses with immediate treatment of clinically isolated disease but no improvement in disability outcomes, data from a randomized trial showed.

Patients who received immediate treatment with interferon had a 36% lower 10-year odds for progression to clinically definite MS and lower relapse rates at five and 10 years.

However, disability scores, MRI-visible lesions, and the rate of progressive disease at 10 years all did not differ between patients randomized ...
Read more : Mixed results seen for immediate MS treatment | Views : 2605 | Replies : 0

Avonex side efects two times in the week


I'm writing from Poland. Sorry for my English.
My girl started Avonex 3 months ago. She always takes shot on Friday evening. Then later and all Saturday has always side effects. She takes something like Tylenol or Advil. Next day - on Sunday always everything is good.
Now I'm writing problem, something what disturb us. Sometimes (two - three times in month) in one day since Monday do Thursday she has come back side ...
Read more : Avonex side efects two times in the week | Views : 2398 | Replies : 2

Feet and Ankle Swelling

I am new to the website, diagnosed 6 years ago been on Avonex since day one. Flue like symptoms early on but have lessened over the years, lately just tired & achy the day after the shot. This week my ankles and feet are extremely swollen it has happened before but did not notice if it coincided with the shot.
Anyone else have this?
Read more : Feet and Ankle Swelling | Views : 2432 | Replies : 1

EU regulators approve Avonex pen


Biogen Idec Inc. said Tuesday that European uni0n regulators approved an injectable pen version of its multiple sclerosis drug Avonex.

The Avonex Pen is approved for patients who have experienced the first symptoms of MS, or who have the relapsing form of the disease. The pens are single-use pens with a dose that lasts one week. Biogen Idec said it will start making the pens available in Europe over the next few weeks.

Avonex ...
Read more : EU regulators approve Avonex pen | Views : 2530 | Replies : 0

Positive data from Avonex dose titration study reported


Biogen Idec has announced the findings from a randomized, multicenter, dose-blinded clinical trial that evaluated the effect of Avonex®(interferon beta-1a) dose titration, or gradual dose escalation, on flu-like symptoms associated with the therapy.

The data demonstrated that dose titration with Avonex over three weeks at the initiation of treatment resulted in a 76 percent reduction in flu-like symptom severity between pre-injection and the four-six-hour post-injection time point versus no titration (p<0.001).... Read More - ...
Read more : Positive data from Avonex dose titration study reported | Views : 2989 | Replies : 2


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