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A board to discuss the Multiple Sclerosis modifying drug Avonex

Genetic sensitivity to interferon-beta

My father recently had a DNA profile done and one of the traits that came back was a significantly increased sensitivity to interferon beta.

"This study examined 199 patients from Spain with clinically diagnosed relapsing-remitting multiple sclerosis who had received interferon beta treatment for at least two years. The authors classified patients as “non-responders” if, over the two year period of interferon beta treatment, they had two or more disease relapses, or if their Expanded ...
Read more : Genetic sensitivity to interferon-beta | Views : 1569 | Replies : 1


Mixed results seen for immediate MS treatment

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Multiple sclerosis patients had fewer relapses with immediate treatment of clinically isolated disease but no improvement in disability outcomes, data from a randomized trial showed.

Patients who received immediate treatment with interferon had a 36% lower 10-year odds for progression to clinically definite MS and lower relapse rates at five and 10 years.

However, disability scores, MRI-visible lesions, and the rate of progressive disease at 10 years all did not differ between patients randomized ...
Read more : Mixed results seen for immediate MS treatment | Views : 1837 | Replies : 0


Avonex side efects two times in the week

Hi,

I'm writing from Poland. Sorry for my English.
My girl started Avonex 3 months ago. She always takes shot on Friday evening. Then later and all Saturday has always side effects. She takes something like Tylenol or Advil. Next day - on Sunday always everything is good.
Now I'm writing problem, something what disturb us. Sometimes (two - three times in month) in one day since Monday do Thursday she has come back side ...
Read more : Avonex side efects two times in the week | Views : 1617 | Replies : 2




Feet and Ankle Swelling

I am new to the website, diagnosed 6 years ago been on Avonex since day one. Flue like symptoms early on but have lessened over the years, lately just tired & achy the day after the shot. This week my ankles and feet are extremely swollen it has happened before but did not notice if it coincided with the shot.
Anyone else have this?
Read more : Feet and Ankle Swelling | Views : 1711 | Replies : 1


EU regulators approve Avonex pen

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Biogen Idec Inc. said Tuesday that European uni0n regulators approved an injectable pen version of its multiple sclerosis drug Avonex.

The Avonex Pen is approved for patients who have experienced the first symptoms of MS, or who have the relapsing form of the disease. The pens are single-use pens with a dose that lasts one week. Biogen Idec said it will start making the pens available in Europe over the next few weeks.

Avonex ...
Read more : EU regulators approve Avonex pen | Views : 1989 | Replies : 0


Positive data from Avonex dose titration study reported

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Biogen Idec has announced the findings from a randomized, multicenter, dose-blinded clinical trial that evaluated the effect of Avonex®(interferon beta-1a) dose titration, or gradual dose escalation, on flu-like symptoms associated with the therapy.

The data demonstrated that dose titration with Avonex over three weeks at the initiation of treatment resulted in a 76 percent reduction in flu-like symptom severity between pre-injection and the four-six-hour post-injection time point versus no titration (p<0.001).... Read More - ...
Read more : Positive data from Avonex dose titration study reported | Views : 2182 | Replies : 2


Avonex pen now available for Canadian MS patients

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Biogen Idec Canada Inc announced AVONEX® PEN™ is now available for patients with relapsing multiple sclerosis (MS) and patients with a single demyelinating event in Canada.

“We are delighted to make Avonex Pen available to MS patients in Canada. For many patients, Avonex is the therapy ... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1900
Read more : Avonex pen now available for Canadian MS patients | Views : 1993 | Replies : 0


which injectable?

For those that don't hang out on the stem cell board, I have been trying for a couple weeks to get approved for Dr. Burt's Mist stem cell treatment for my newly diagnosed MS.
I had several discussions today with the folks in charge of the study. The bottom line is that they told me to come get checked out, and then told me that they wouldn't take me for 6months. I must be on ...
Read more : which injectable? | Views : 1709 | Replies : 3


worse side effects on rainy days?

Was diagnosed with ms last year in april. Have been on avonex since then. Have recently experienced that the side effects following the shot are worse if its raining. Also there is kind of pain/weakness in the limbs when its cloudy/raining. Anyone with similar experience and the knowledge about the possible cause for the same.
Read more : worse side effects on rainy days? | Views : 2037 | Replies : 1


 

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