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A board to discuss the soon-to-be released drug Campath as a treatment for Multiple Sclerosis

finally OUT part 1

Well the fine folks at Genzyme have given me the boot. I am apparently not treatment naive because of the 28 days I was in the open label with Tovaxin and I am not eligible for Care 2 because I wasn't on treatment??? The clinical Neuro went to bat for me and still, NO. The only thing more frustrating than MS is trying to find a useful treatment for it. I would like to once ...
Read more : finally OUT part 1 | Views : 1845 | Replies : 9

Campath feedback please

Hello all,

I am new to the Campath forum but some of you may recognize me from the Tovaxin forum. I want to for some feedback from you folks, especially the those who have gone through the Campath treatment. Below the paragraph with my questions is a description of my situation if that helps with your input.

After the Tovaxin study was shut down, the Campath folks finally decided to let us Tovaxin folks into ...
Read more : Campath feedback please | Views : 4680 | Replies : 17

finally in part 2

Signed consent forms today (Doc scared the shit out of me). A question to those of you in the know, how long after treatment did it take to get back to an OK physical place, i.e. work, hobbies, general activities etc.?
Read more : finally in part 2 | Views : 1681 | Replies : 7

Finally in

After what seems like months of waiting for the call and the issues related to my participation in the Tovaxin trial, I finally got the OK from my nearest Campath site. I have been doing the standard paper faxing etc., weighing the pro's and con's (mainly that I don't want to be on Rebif) and trying to make damn sure this is the right avenue. I have to be in Care One which improves my ...
Read more : Finally in | Views : 3681 | Replies : 25

Another alemtuzamab labrat

I had my initial visit today for the CARE MS II trial and have officially met the criteria. I will know on Feb 23 whether I get alemtuzamab or rebif. Does anyone know why we have to have the tb test. I get my results read on Monday.

Read more : Another alemtuzamab labrat | Views : 15829 | Replies : 84

I am in the trial, but got questions

I have been accepted into the trial after a battery of tests the other day. The coordinator said to stop the Rebif crap from hell that i am on now to start the 28 day wash out period. then he said that the results of the randomization will not be known until the day of the first treatment. Only then will I know that I was selected for the Campath arm, not the Rebif arm. ...
Read more : I am in the trial, but got questions | Views : 1414 | Replies : 2

Article on Campath

Positve, but realistic article on effectiveness of Camapth.

Buzz around Campath proof-of-concept trial in MS 16 January 2009

When news broke in October that an approved cancer therapy had, for the first time, halted the progress of multiple sclerosis (MS), excitement was tangible among clinicians and patient groups. The phase 2 study's results are certainly unprecedented in MS. But whether Campath (alemtuzumab), a monoclonal antibody (mAb) already approved to treat leukemia, actually 'reverses' MS, ...
Read more : Article on Campath | Views : 1529 | Replies : 3

Day 4 of my campath infusion!

I'm on day 4 and it's going MUCH better than expected. I was diagnosed in Sept 08 and started campath off-label Jan 5, 2009. Only minor side effect was hives, which goes away with benadryl, and other antihistimines. no major aches, pains other than some tiredness and aches day 1. Each day takes about 5 hours in the infusion area. I am very hopeful for the future and thrilled i was able to get infusions. ...
Read more : Day 4 of my campath infusion! | Views : 1682 | Replies : 4

Campath research articles

First thing - happy New Year.

A belated Christmas present for Lyon and others.

Here is a link to Dr Alasdair Coles which give an overview of his work with Campath for MS. If you go down the page there is a section called Key publications. The first publication is the research article on the 3 year Phase II trial (CAMMS 223) - open the PDF file. Worth printing out as it is quite long ...
Read more : Campath research articles | Views : 1594 | Replies : 4

A few Campath questions

Hello All,
As a recent transfer from the Tovaxin trial, I, like some others am considering the Campath trial. Thanks for all the posted info and videos on this site. A few questions; is Campath considered a true re-boot like Revimmune? Unlike Revimmune, I do not hear the term Chemotherapy used to describe Campath and yes I have watched all the videos and have read as much as I can but still wonder exactly what ...
Read more : A few Campath questions | Views : 4379 | Replies : 19


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