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A board to discuss the soon-to-be released drug Campath as a treatment for Multiple Sclerosis

New significant data for Campath in MS

Significant percentage of MS patients receiving Alemtuzumab in Genzyme's phase 2 trial remain free of clinically-active disease - ... ageid/1307
Read more : New significant data for Campath in MS | Views : 2023 | Replies : 2

Campath 12mg - 2nd

Hello everybody
I'm writing here in behalf of my friend from Poland. He's in his 20's, asked me for help to translate. He's looking for anybody who already took second dose (second part?) of 12mg Campath. He would like to know is there any side effects. Please share your opinions. It's really tough to get any info at Polish discussion forums, that's why he decided to ask for info here. Thank you for any help.
Read more : Campath 12mg - 2nd | Views : 2325 | Replies : 6

Month 24

My study is Care MS 1. This is Month 24. entering into the extension phase and just learned I received the 25mg dose both times. My MRI showed no new changes. My blood is stable: lymphs are low but within normal parameters. I didn't ask @ the levels on the CD 54+ (or whatever..they test a few and i don't have that part memorized-if u rly want to know how low they go w/ campath, ...
Read more : Month 24 | Views : 1570 | Replies : 1

Spotlight on Alemtuzumab

A good summary of the Campath research to date, that includes statistics for the early trials of the drug between 1991 and 2002 (along with the widely published Phase II trial results). The pdf linked below is much easier to read!


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Spotlight on Alemtuzumab

Alemtuzumab, formally known as Campath-1H, is a humanized monoclonal antibody directed against CD52, a protein on the surface of lymphocytes and monocytes with unknown function. A single ...
Read more : Spotlight on Alemtuzumab | Views : 2356 | Replies : 2

AAN abstract

Dear all,

There are a few Alemtuzumab (Campath) abstracts being presented at the AAN conference in April.

As someone who has had their two infusions - the last being 27 months ago, it's quite comforting that the treatment effect seems to hold good for the majority of patient for at least four years after treatment. ... 0L_P04.213

I now have an annual MRI and a six-monthly check-up. My ...
Read more : AAN abstract | Views : 1675 | Replies : 4



My MS has gradually worsened (walking more unstable) over a year, and my neuro suggested I look at Novantrone as an option -- see ehat 3 doses woul;d do etc.

I was wondering though, if I went for this option would it complicate using Campath -- or Revimmune -- in the future? Was thinking in terms of supressed immunity with a chemo drug and then problems using a monoclonal antibody.

Any input welcome! Also ...
Read more : Campath/Novantrone | Views : 1388 | Replies : 0

Licence for Campath?


Any of you guys know when Campath is likely to become a licenced/approved treatment in the UK and the US?

Have been reading different dates -- 2010, 2011, 2012 and so on.


Read more : Licence for Campath? | Views : 2281 | Replies : 10


Anybody heard results on female fertility and campath? sorry if i've asked before. I'm not getting any younger! Thanks.
Read more : Fertility | Views : 5004 | Replies : 15

Month 21-Two rounds of campath

Sorry guys, I've moved on to CCSVI !!
I mean, that's where I've moved my proverbial eggs to.
I think campath slowed down a wicked downward spiral but there's something out here that's keeping me down. Or I mean my wbc attack ON. whatever i don't know, but campath's not enough. i have to admit my diet is crap...but beyond that i don't know what else to do to to get better.
I accepted, bought ...
Read more : Month 21-Two rounds of campath | Views : 1872 | Replies : 6

Campath worked great for me for 6 months, then RELAPSE CITY

I was in the CAMMS323 trial and I received Campath (although I still do not know the dosage). I was only diagnosed with RRMS for one year and 2 months before going into the trial. I am currently at month 11, and will likely be pulled out of the study.

I tolerated the infusions very well, and even continued to improve for 6 months after the initial set of infusions, but right around the 6 ...
Read more : Campath worked great for me for 6 months, then RELAPSE CITY | Views : 4631 | Replies : 23


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