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A board to discuss the soon-to-be released drug Campath as a treatment for Multiple Sclerosis

Campath worked great for me for 6 months, then RELAPSE CITY

I was in the CAMMS323 trial and I received Campath (although I still do not know the dosage). I was only diagnosed with RRMS for one year and 2 months before going into the trial. I am currently at month 11, and will likely be pulled out of the study.

I tolerated the infusions very well, and even continued to improve for 6 months after the initial set of infusions, but right around the 6 ...
Read more : Campath worked great for me for 6 months, then RELAPSE CITY | Views : 4268 | Replies : 23


Campath round one 6 weeks ago

So far no side effects to speak of and to be honest not real sure what to expect. I went into this without any real expectations. I just trusted my doctors to lead me in a direction that I assume they are certainly more knowledgeable about. Now I have found this site and am curious as to any stories pertaining to possible changes specifically in regards to bladder issues. My most annoying MS symptom is ...
Read more : Campath round one 6 weeks ago | Views : 1625 | Replies : 3


HELLO EVERYONE!! JUST GOT CAMPATH 2 MONTHS AGO!!!

I am so glad that i found this site...........I am two months in and feeling a lil crappy...so glad to read all of these post because it has helped me to understand how this medication works..I have been told by my doctor that it does take time, so now that I am able to get a feel for how much time I feel renewed! Clinging on to hope that I will have wonderful results like ...
Read more : HELLO EVERYONE!! JUST GOT CAMPATH 2 MONTHS AGO!!! | Views : 3818 | Replies : 15


5 month update

well ive past the 5 month mark. no relapses so far, i think... no real changes in symptoms. my chronic sleepiness since december is decreasing somewhat, but that may be normal for relapsing remitting since it has been 9 months since that symptom came up. but all my old symptoms are still the same. i still can go to the gym 5 days a week and work out for an hour. (almost have my eyes ...
Read more : 5 month update | Views : 1303 | Replies : 0


awesome results

Genzyme Says Follow-up Data From Alemtuzumab Phase 2 Trial Continues To Show Lasting Benefits - Update
9/11/2009 1:32 PM ET





EnCana Revives Plan To Split Into Two Companies - Update
(RTTNews) - Friday, biotechnology company Genzyme Corp. (GENZ: News ) said that four-year follow-up data from its completed Phase 2 multiple sclerosis trial continued to show durable reductions in relapse rate and sustained accumulation of disability three years after the majority of patients received their ...
Read more : awesome results | Views : 6354 | Replies : 36


Flu shot, post campath: Yes or no?

Okay, so I am an RN. The Dept of Health in my county has mandated all healthcare workers to get vaccinated, or else have a doc's note.
I asked my research nurse, and she said okay. Then I brought it up again, and now she doesn't remember saying okay. She says that the study people say "No vaccinations!".
It's a good thing I waited a few days on the shot!
What have the rest of ...
Read more : Flu shot, post campath: Yes or no? | Views : 1973 | Replies : 6


Grumpster got ITP now

Well it has been a long time sice I posted. I hit the 6 month mark recently. I had some immediate adverse events after the treatment, but then I have been doing well neurologically actually really pretty good. My balance, gait, and strength have been better. My vertigo that lasted > 1 year has subsided to very managable levels where it was at one point bringing me to the brink of the end of life ...
Read more : Grumpster got ITP now | Views : 2823 | Replies : 10


Meet a man starting 2nd year of Campath

While I was getting my Tysabri Infusion we met a man and his wife who came in to say hello the infusion nurses. He said he would be back next week to start year 2 of Campath.

I asked if he thought it helped and he said definately, although he still could not tolerate the heat and humidity at all. He was excited to have year 2 infusions.

The infusion nurse also said they we ...
Read more : Meet a man starting 2nd year of Campath | Views : 1932 | Replies : 5


Change in lymphocyte gene expression induced by Campath-1H

Change in lymphocyte gene expression induced by Campath-1H treatment of multiple sclerosis
J.A. Somerfield, J.L. Jones, V.H. Robertson, D.A.S. Compston, A.J. Coles (Cambridge, UK)

Objectives: Campath-1H, a humanised monoclonal antibody to CD52, causes profound lymphopenia. It significantly reduces the relapse rate of multiple sclerosis and, intriguingly, results in reduced EDSS scores at 36months. This study aims to identify changes in peripheral lymphocyte gene expression associated with this improvement in disability after Campath-1H treatment.
Methods: Blood ...
Read more : Change in lymphocyte gene expression induced by Campath-1H | Views : 1468 | Replies : 1


Second round of infusions start tomorrow

Hey everyone,
I start my second round of campath tomorrow. I can't believe it has been a year already. Only three days this time. I hope everyone is doing well. I am anticipating an uneventful few days of sitting in the office with an IV in my hand/arm. I will post anything of importance over the next couple of days.
Read more : Second round of infusions start tomorrow | Views : 3472 | Replies : 17


 

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