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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

CCSVI procedure failed...

Hi All,

I had my CCSVI procedure done in Dayton 2 weeks ago and I haven't experienced any good results from it... In the beginning the headaches were weaker, but now everything got back to the situation it was before...

I was looking at the images again and it looks like I have a stenosis on one of my sigmoid sinus. I saw that when I was reviewing the images with the doctor and he ...
Read more : CCSVI procedure failed... | Views : 476 | Replies : 7




CCSVI in MS reviews

CCSVI theory is not dead. Just looking for its place in the big picture.

Neuroinflammation (book). Review.

Chapter 29 - The Contribution of Extra Cranial Venous Drainage to Neuro-Inflammation in Multiple Sclerosis

https://www.sciencedirect.com/science/a ... 7095000363

Abstract

The role of the extracranial veins in the pathogenesis of inflammatory neurological/neurodegenerative diseases remains largely unknown and under-investigated.

A condition named chronic cerebrospinal venous insufficiency (CCSVI) strikes the main extracranial veins and determines ...
Read more : CCSVI in MS reviews | Views : 616 | Replies : 0


Five-Year Longitudinal Study of Neck Vessel Area

Five-Year Longitudinal Study of Neck Vessel Cross-Sectional Area in Multiple Sclerosis

http://www.ajnr.org/content/early/2018/07/26/ajnr.A5738

BACKGROUND AND PURPOSE: Alterations of neck vessel cross-sectional area in multiple sclerosis have been reported. Our aim was to investigate the evolution of the neck vessel cross-sectional area in patients with MS and healthy controls during 5 years.

CONCLUSIONS: For 5 years, patients with MS showed significant cross-sectional area decrease of all major neck vessels, regardless of ...
Read more : Five-Year Longitudinal Study of Neck Vessel Area | Views : 714 | Replies : 0


Zamboni: Review of the Brave Dreams trial

Extracranial Veins in Multiple Sclerosis: Is There a Role for Vascular Surgery?

https://www.ejves.com/article/S1078-5884(18)30387-3/fulltext

Conclusions and Perspectives

From a pathophysiological point of view the post hoc analysis reported above suggests a role of impaired extracranial venous flow in lesion development in patients with MS, as well as the probability of significant advantages when the brain outflow is restored. This finding continues to support the CCSVI hypothesis and the contribution of the jugular flow to cerebral ...
Read more : Zamboni: Review of the Brave Dreams trial | Views : 630 | Replies : 0


Cardiovascular conditions are as common in those with MS

Cardiovascular conditions are as common in those with demyelinating diseases (multiple sclerosis, neuromyelitis optica and transverse myelitis)

https://www.researchgate.net/profile/Pa ... elitis.pdf

Background: Cardiovascular conditions are associated with poorer outcomes in multiple sclerosis (MS). Whether
the burden of cardiovascular conditions differs between those with demyelinating disease and unaffected controls
is not clear. The objective of this study is to investigate the burden and age of onset of cardiovascular
conditions in a ...
Read more : Cardiovascular conditions are as common in those with MS | Views : 634 | Replies : 0


recent zamboni interview (may 2018)

It is in italian. Can somebody translate?

https://www.youtube.com/watch?v=jgKZun8umEw
Read more : recent zamboni interview (may 2018) | Views : 650 | Replies : 2


MS B-cells in vitro do weird things. CCSVI link?

This is an article that I am reading slowly, as I do not understand most of the things it says. But the summary is that MS B-cells do weird things. Something that was already suspected, because B-cells depletion with anti-CD20 MABs is the best thing we have at this time against MS.

It seems that the researchers have extracted B-cells from MS patients and infected them with the Epstein-Barr virus EBV. After that, it seems ...
Read more : MS B-cells in vitro do weird things. CCSVI link? | Views : 834 | Replies : 0


Cerebral Blood Flow Changes in Multiple Sclerosis

Cerebral Blood Flow Changes in Multiple Sclerosis and Neuromyelitis Optica and Their Correlations With Clinical Disability.

https://www.ncbi.nlm.nih.gov/pubmed/29780351

Abstract

Distinguishing relapsing-remitting multiple sclerosis (RRMS) and neuromyelitis optica (NMO) is clinically important because they differ in prognosis and treatment. This study aimed to identify perfusion abnormalities in RRMS and NMO and their correlations with gray matter volume (GMV) atrophy and clinical parameters. Structural and arterial spin labeling MRI scans were performed ...
Read more : Cerebral Blood Flow Changes in Multiple Sclerosis | Views : 793 | Replies : 0


red blood cells have altered metabolism

red blood cells have altered metabolism

https://search.proquest.com/openview/25 ... 750&diss=y

Glucose transporter 1 (GLUT1) is the main glucose transporter on RBCs, and all metabolism within theRBC involves glucose.RBC GLUT1 content was used as a measure of RBC metabolism, andelevated RBC GLUT1 content is proposed to be associated
with increased cell metabolism.RBCs obtained from MS patients contained 23.3± 4.8% more GLUT1 than control RBCs, while T1D RBCs
contained 23.6± 4.2% less ...
Read more : red blood cells have altered metabolism | Views : 788 | Replies : 0


 

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