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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Looking Dr. Marian Simka's information

I have been diagnosed with MS for 30 years but it wasn't until 10 years ago I started having walking difficulties. After trying what pharmaceuticals have to offer, I am medication free and I strongly believe and can see a connection with Dr. Zamboni and Dr. Marian Simka with my symptoms. Does anyone know how to contact any of them? --Betsy
Read more : Looking Dr. Marian Simka's information | Views : 155 | Replies : 5


Propose for TED talk

Folks,

I am sure many of you are aware of TED talk. If some of you have not, I do suggest you listening to some of the topics on Biology, Health, Brain etc. The insight TED provides is just incredible. The other day, I was listening to this speaker who was explaining why sleep is essential (http://www.ted.com/talks/jeff_iliff_one ... ht_s_sleep) and some of the findings were simply an eye opener ...
Read more : Propose for TED talk | Views : 111 | Replies : 1


CCSVI: How RRMS becomes SPMS

The French Neurologist Jean-Martin Charcot, practicing at the Parisian la Pitié-Salpetrière hospital, first described Multiple Sclerosis (Sclérose en Plaques) in 1868. Among other things, he defined MS as a “rigidity disorder”. He thus set the tone in the Neurology profession of an unfortunate prejudice towards MS patients by claiming their “rigidity” symptoms were psychological in origin - signs of neurotic (usually female) hysteria. I now believe it is just this rigidity which is at the ...
Read more : CCSVI: How RRMS becomes SPMS | Views : 145 | Replies : 0


Sleep restriction impairs blood-brain barrier function

J Neurosci. 2014 Oct 29;34(44):14697-706. doi: 10.1523/JNEUROSCI.2111-14.2014.

Sleep restriction impairs blood-brain barrier function.

He J1, Hsuchou H1, He Y1, Kastin AJ1, Wang Y1, Pan W2.
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Abstract
The blood-brain barrier (BBB) is a large regulatory and exchange interface between the brain and peripheral circulation. We propose that changes of the BBB contribute to many pathophysiological processes in the brain of subjects with chronic sleep restriction (CSR). To achieve CSR that mimics a common pattern of ...
Read more : Sleep restriction impairs blood-brain barrier function | Views : 150 | Replies : 2


Blood flow is worse in people with MS (Oct 2014 research)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216015/
Results

85 RR-MS, 83 PP-MS and 82 healthy controls were included. ΔCVF was negative in 45/85 (52.9%) RR-MS, 63/83 (75.9%) PP-MS (p = 0.01) and 11/82 (13.4%) controls (p<0.001), while MFVs on both MCAs in sitting position were significantly reduced in RR-MS and PP-MS patients than in control, particularly in EDSS≥5 subgroup (respectively, 42/50, 84% vs. 66/131, 50.3%, p<0.01 and 48.3±2 cm/s vs. 54.6±3 cm/s, p = 0.01). ...
Read more : Blood flow is worse in people with MS (Oct 2014 research) | Views : 147 | Replies : 2




CCSVI Treatment for Primary Progressive MS?

Hi sorry if Im replicating (I did do a search and go to the newbie section first).

My sister has Primary Progressive MS, I have just been to see a consultant who does CCSVI, however he said he had little experience of doing CCSVI on primary progressive MS, although they have had some positive results for people with other types of MS, he had only done one operation on one patient with Primary Progressive MS ...
Read more : CCSVI Treatment for Primary Progressive MS? | Views : 338 | Replies : 12


Old paper from Hans Lassman

I have just found a paper from Hans Lassman from 2007. This author is quite important because he colaborates in the forefront of research, with Lucchinetti, Vanda Lennon and the people from the Mayo Clinic.

Though he has never used the term CCSVI this is what he writes in his paper:

Taken together, all these studies agree that the most initial
tissue changes in focal white matter lesions occur on a
background of mild perivenous ...
Read more : Old paper from Hans Lassman | Views : 243 | Replies : 1


study of the effect of hemoglobin on myelin

Just for those of you that love literature, here comes the next chapter of "Hemosiderin damage"

In vitro study of the direct effect of extracellular hemoglobin on myelin components.

http://www.ncbi.nlm.nih.gov/pubmed/25463632

Abstract

There is a relationship between cerebral vasculature and multiple sclerosis (MS) lesions: abnormal accumulations of iron have been found in the walls of dilated veins in MS plaques. The sources of this iron can be varied, but capillary ...
Read more : study of the effect of hemoglobin on myelin | Views : 362 | Replies : 2


New study: 83% of 552 pwMS have CCSVI

Using Zamboni's doppler technology---and including intrinsic and external vein compression--
"Balloon and go" is not the best treatment protocol. Patients must be individually assessed and treated. Most have a combo platter of internal and external vein issues. Jeff had external compression, which is why he was stented. Other vascular doctors use vein grafts, release surgery on muscles, atlas adjustments, and other methods to deal with external compression.
cheer


AIM: The aim of the present study ...
Read more : New study: 83% of 552 pwMS have CCSVI | Views : 620 | Replies : 11


 

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