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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Dr Paul Thibault - current position on CCSVI

From CCSVI / CCSVO specialist Dr Paul Thibault :

The concern I have is that people (medical doctors, patients, and the general public) will become disillusioned by the many studies (including Zamboni et al), which refute the use of venoplasty to achieve a "cure" for MSi. Zamboni has highlighted the connection between MS and a chronic venous disease, which I appreciate. However, since 2011 I have suspected his theory that venous obstructions cause demyelinationi (due ...
Read more : Dr Paul Thibault - current position on CCSVI | Views : 278 | Replies : 0


CCSVI dead - surely an apology needed from Cheerleader

no ifs, no buts.

CCSVI is dead and buried. It was fakery and bad science and promoted by Cheerleader.

MSers wasted time and money.

If it really worked (now around for 10 years) this site would have shut down as readers would have all experienced the claimed miracles.

Next time you aggressively promote a treatment - check the facts Cheerleader.


http://multiple-sclerosis-research.blog ... peace.html
Read more : CCSVI dead - surely an apology needed from Cheerleader | Views : 692 | Replies : 16




Paper: Angioplasty of internal jugular and azygous vein

Percutaneous angioplasty of internal jugular and azygous veins in patients with chronic cerebrospinal venous insufficiency and multiple sclerosis: preliminary results for a randomized controlled trial

Source: https://etd.adm.unipi.it/t/etd-06192017-102412/

Conclusion:

Study’s aim is to assess the efficacy of PTA on CCSVI and MS patients’ functional disability. Endovascular treatment of the IJV is proven to be a safe procedure (major complication <0,05%) with no significant improvement of IJV flow haemodynamic parameters and ...
Read more : Paper: Angioplasty of internal jugular and azygous vein | Views : 372 | Replies : 0


astronaut eyes

More information on the damage to astronaut eyes during long term spaceflight. It was on CNN's website so probably fake news. Just kidding. Thought this was interesting, the idea that eyes act like a pressure release valve to a brain that has too much cerebrospinal fluid pressure.

http://www.cnn.com/2017/11/01/health/br ... index.html

Given the connection between the eye, the optic nerve and the brain, combined with the fluid shift astronauts experience, ...
Read more : astronaut eyes | Views : 428 | Replies : 1


Could it be that CCSVI just makes MS worse?

Could it be that CCSVI just makes MS worse?

This is an idea that came to me after reading an article named "The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766379/). I enclose here some quotes:

"Their location (of the lesions), shape and patterns of active demyelination are compatible with the view that they are driven by a soluble factor, produced in the inflammatory infiltrates of ...
Read more : Could it be that CCSVI just makes MS worse? | Views : 570 | Replies : 6


vascular impact in brain volume and lesion load

The impact of vascular risk factors on brain volume and lesion load in patients with early multiple sclerosis

http://journals.sagepub.com/doi/abs/10. ... 8517736149

Conclusion:

VRF are associated with lower brain volume already in early MS but do not lead to increased brain volume loss during 3.5 years of follow-up.
Read more : vascular impact in brain volume and lesion load | Views : 378 | Replies : 0




brain drain

https://www.nih.gov/news-events/news-re ... our-brains

The question in my mind is: is it nocturnal (i.e. during REM sleep). If it is, (the mice drained during diurnal sleep -- i.e., during the day) we may have a way to deal with Alzheimers -- by getting good sleep!

In fact, it should be a goal of the makers of sleeping medication to trigger the brain's "rinse cycle". Are you listening, drug manufacturers?
Read more : brain drain | Views : 659 | Replies : 5


New association of vein anomalies and MS found, Sept. 2017

New association of vein anomalies and MS found, Sept. 2017. I put the date because this has been reported already before.

I would say that is getting clear that MS is not a single disease. Some cases are clearly of vascular origin, though some others are not. Look at this.

Association of Developmental Venous Anomalies with Demyelinating Lesions in Patients with Multiple Sclerosis

http://www.ajnr.org/content/early/2017/09/14/ajnr.A5374

SUMMARY: We present 5 cases ...
Read more : New association of vein anomalies and MS found, Sept. 2017 | Views : 386 | Replies : 0


 

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