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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

McGuckin disciplined in TX for CCSVI procedures

http://www.yourhoustonnews.com/memorial ... 1a460.html
McGuckin, James Frederick, Jr., M.D., Lic. No. N1760, Philadelphia, PA

On June 10, 2016, the Board and James Frederick McGuckin, Jr., M.D., entered into an Agreed Order requiring Dr. McGuckin to comply with all terms as required by the Agreed Order issued by the Washington Medical Quality Assurance Commission. Dr. McGuckin shall not perform angioplasty and stenting procedures of the venous system for chronic cerebrospinal venous ...
Read more : McGuckin disciplined in TX for CCSVI procedures | Views : 1008 | Replies : 7


FDA approves bioresorbable stent

The FDA has recently approved a bioresorbable stent. Could these one day be used for CCSVI?

http://www.peoplespharmacy.com/2016/07/ ... ike-magic/

First Stent That the Body Can Resorb:

Now, the FDA has approved the first stent made of a polymer that gradually dissolves in the body. The bioresorbable vascular scaffold system disintegrates in about three years, leaving no trace. It appears to be roughly as effective as standard stents in preventing ...
Read more : FDA approves bioresorbable stent | Views : 411 | Replies : 1


Go Fund Me

http://gofundme.com/2bhxt6rg is the url for my project.
Read more : Go Fund Me | Views : 527 | Replies : 2


Gene NR1H3 recently discovered interacts with endothelium

This month was published that a mutation in gene NR1H3 was heavily related to familial PPMS. The big news for CCSVI is that this gene is involved in the production of the protein LXRA, and if we look in wikipedia:

https://en.wikipedia.org/wiki/Liver_X_receptor_alpha

we find that it interacts with EDF1, other protein involved in the endothelium.

https://en.wikipedia.org/wiki/EDF1

Besides, LXRA is also related to the metabolism ...
Read more : Gene NR1H3 recently discovered interacts with endothelium | Views : 673 | Replies : 4


Advanced CCSVI diagnostic center will be opened in Ferrara

According to this article, an advanced CCSVI diagnostic center will be opened in a few months in Ferrara:

http://www.osservatoriomalattierare.it/attualita/10599-ccsvi-nascera-a-ferrara-centro-pubblico-di-diagnosi-avanzata

This is translated from an original article in Italian, and I think that a little may be lost in the translation. I found the article on the internet:

CCSVI, will be born in Ferrara center of advanced diagnostic audience

Author: Drafting, May 20, 2016

An advanced CCSVI diagnostic center will be opened in a few months ...
Read more : Advanced CCSVI diagnostic center will be opened in Ferrara | Views : 541 | Replies : 2


Central Vein Sign on SWI is special in MS

The Central Vein Sign on SWI at 3T MRI Differentiates Multiple Sclerosis from Neuromyelitis Optica

http://www.neurology.org/content/86/16_ ... .147.short


Abstract

OBJECTIVE: To assess the discriminatory value of the central vein sign (CVS) on susceptibility-weighted imaging (SWI) acquired on a clinical scanner (3T) between neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS).

BACKGROUND: It would be useful to identify brain magnetic resonance imaging (MRI) features that help to differentiate between ...
Read more : Central Vein Sign on SWI is special in MS | Views : 480 | Replies : 0


Italian team studies Chiropractic care for MS CCSVI

Hello Dr. Flanagan:

Hugo Macia (his blog - http://www.secretosdelaesclerosismultip ... pot.com.es.)
has just sent me this PubMed study which implies that Neurologists are finally considering the "mechanical" aspect of CCSVI. The Italians are apparently the most interested because one of their own (Dr. Zamboni) proposed the CCSVI theory for MS. How would you undertake, improve on, such a study?

see http://www.ncbi.nlm.nih.gov/m/pubmed/26228993/.

Preliminary results ...
Read more : Italian team studies Chiropractic care for MS CCSVI | Views : 625 | Replies : 3


Dr. Haacke: int'l imaging research shows CCSVI in Parkinsons

https://www.facebook.com/CCSVI-Alliance ... 427429118/
Dr Mark Haacke spoke briefly about international imaging research (of which he is a principal investigator) shows CCSVI in Parkinson's. He will be sharing the study in his presentations.

Well that is interesting! More info please! :)
Read more : Dr. Haacke: int'l imaging research shows CCSVI in Parkinsons | Views : 600 | Replies : 0


More about pattern III

Pattern III in MS lesions is a specific kind of demyelination that looks hypoxic, and therefore it could be more related than others to CCSVI. Pattern III is known as "distal oligodendrogliopathy" because oligodendrocytes die in that specific way.

A previous text (available at http://www.ajnr.org/content/27/5/954.full) used to say that lesions are similar to the early stages of WM ischemia and may therefore reflect hypoxic WM damage. A pathologic process ...
Read more : More about pattern III | Views : 493 | Replies : 1


venous congestion in MRI hypotense black holes

Not sure if this applies to MS, but just in case ...

“Venous congestion” as a cause of subcortical white matter T2 hypointensity on magnetic resonance images

http://www.annalsofian.org/preprintarti ... 978;type=0

Subcortical T2 hypointensity is an uncommon finding seen in very limited conditions such as multiple sclerosis, Sturge-Weber syndrome, and meningitis. Some of the conditions such as moyamoya disease, severe ischemic-anoxic insults, early cortical ischemia, and infarcts are of “arterial ...
Read more : venous congestion in MRI hypotense black holes | Views : 542 | Replies : 0


 

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