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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.


More about NPH. A Pulse Wave Encephalopathy?

This time I have found the paper of the week faster than Cece and Cheer !!!!


Is There A Pulse Wave Encephalopathy Component To Multiple Sclerosis?
http://www.ncbi.nlm.nih.gov/pubmed/25760216

Abstract
The dominant hypothesis in multiple sclerosis is that it is an autoimmune disease; however, there is considerable evidence that the immune attack on myelin may be secondary to a cytodegenerative event.

Furthermore, the immune modulating therapies longest in clinical use, although ...
Read more : More about NPH. A Pulse Wave Encephalopathy? | Views : 452 | Replies : 2


CSF pressure high in children with demyelination

Elevated Cerebrospinal Fluid Opening Pressure in a Pediatric Demyelinating Disease Cohort

http://www.sciencedirect.com/science/ar ... 941500003X

Abstract
Background
Cerebrospinal fluid opening pressure is elevated with central nervous system infection and vasculitis, but has not been studied in inflammatory demyelinating disease. This retrospective study sought to determine whether children with demyelinating disease demonstrate elevated cerebrospinal fluid opening pressure, and to explore possible clinical and radiologic correlates.

Methods
Pediatric patients with acute disseminated ...
Read more : CSF pressure high in children with demyelination | Views : 302 | Replies : 0


Happy Birthday Dr. Sclafani!!!

Happy, Happy Birthday to MH Doc! Have a wonderful day! Just want you to know that Steve & I will be toasting you tonight with a bottle of Port! Thank you for everything you have done for us. We are eternally grateful! Hope you enjoy Napoli, Mr. President. :wink: :wink:
Mum
Read more : Happy Birthday Dr. Sclafani!!! | Views : 366 | Replies : 4


Is TVAM the new kid on the CCSVI block?

Hi all,

How many of you have heard of TVAM?

IT seems to be very similar to CCSVI, but from a marketing perspective its been cleverly dissaciated from MS, so that neuros turn a blind eye to it.

There seems to be one very well know Dr Arata performing the procedure in the states, with good results.

Any of you heard of this procedure?

Thanks,
zjac
Read more : Is TVAM the new kid on the CCSVI block? | Views : 611 | Replies : 7


CCSVI Alliance to attend SIR

CCSVI Alliance will be in attendance at the Society of Interventional Radiology Conference
https://www.facebook.com/pages/CCSVI-Alliance/125892427429118#!/permalink.php?story_fbid=928081243876895&id=125892427429118

Looking forward to the opportunity to speak with the doctors.
Sharon
Read more : CCSVI Alliance to attend SIR | Views : 407 | Replies : 2


Is the CCSVI procedure no longer available in Poland?

Hi all,

Sorry to create a new thread for this but things really are getting more complicated for some unknown reason.

As stated in a previous thread, im trying to contact clinics in Poland and Italy for the CCSVI procedure. I am CIS for MS and a doctor here in spain familiar with CTOS (very closely related to CCSVI) confirmed that blood flow in my right jugular was constricted by about 25%.

I have managed ...
Read more : Is the CCSVI procedure no longer available in Poland? | Views : 696 | Replies : 10


Italian National Epidemiological Observatory for CCSVI

Italian Chronic Cerebrospinal Venous Insufficiency National Epidemiological Observatory methodology and preliminary data

http://www.pagepressjournals.org/index. ... .2014.4707

Abstract

The aim of our work is to describe the Memnet program’s use and potential and to show the data of Italian Chronic Cerebrospinal Venous Insufficiency (CCSVI)-National Epidemiological Observatory (NEO) activity in the first three years (http://www.osservatorioccsvi. org).

From 2011 to 2014, all echo-color- Doppler (ECD) assessments were ...
Read more : Italian National Epidemiological Observatory for CCSVI | Views : 291 | Replies : 0


Cerebral circulation time in MS is double that of normals

Full paper in pdf form.

Blinded study. Cerebral circulation and hypoxia in MS is not correlated with EDSS, disability, lesions or inflammation. It appears to precede all of this---

http://www.plosone.org/article/fetchObj ... tation=PDF

as Dr. Zamboni tweeted---now we need to understand how the venous system might be impacting this slowed cerebral blood flow in MS.


cheer
Read more : Cerebral circulation time in MS is double that of normals | Views : 1313 | Replies : 18


New article about Iron chelators sheds light upon MS

The idea of this article is that Iron can initiate a neurodegeneration which in turn activates microglia.

The importance of this is because NAWM consist mainly in activated microglia, and pre-active lesions, the first stage of a lesion development, are basically clusters of activated microglia.

Therefore according to this model, the MS chain of events would be:

Iron Accumulation -> Activated Microglia -> NAWM and pre-active lesions -> BBB breakdown -> T-cells and B-cells autoimmunity ...
Read more : New article about Iron chelators sheds light upon MS | Views : 666 | Replies : 3


 

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