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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Ashton Embry about the misconducts of some teams

The most recent negative Canadian CCSVI study, lead by University of British Columbia neurologist Dr. Anthony Traboulsee and published in The Lancet, did not utilize the original scientific protocol of Dr. Paolo Zamboni.
http://www.thelancet.com/journals/lance ... X/abstract

This new study displayed even further arrogance and audacity, by deviating from all other published venous and arterial studies, utilizing a false criteria to assess jugular vein stenosis.

Stenosis is routinely measured by ...
Read more : Ashton Embry about the misconducts of some teams | Views : 829 | Replies : 14


MS AND THE VASCULAR CONNECTION

HI FRIENRDS READ THIS PLEASE
http://ccsviinms.blogspot.com.au/2013/1 ... -nest.html
regards
seeva
Read more : MS AND THE VASCULAR CONNECTION | Views : 453 | Replies : 1


PPMS can be passed to mice by CSF. IS PPMS DIFFERENT?

What do you think about this article? Is PPMS a different disease that RRMS/SPMS? Does it have an immune or chemical origin?

If this article is confirmed, I think we are in front of the major discovery in MS since CCSVI. The authors took CSF from PPMS patients and injected it into mice. They developed lesions while the CSF from RRMS patients had mostly no effect.

Progressive multiple sclerosis cerebrospinal fluid induces inflammatory demyelination, axonal ...
Read more : PPMS can be passed to mice by CSF. IS PPMS DIFFERENT? | Views : 1433 | Replies : 21


MS and vascular problems associated

Of course, to have two conditions associated does not imply causality, but I think the association between MS and vascular problems cannot be discussed anymore.

A systematic review of the incidence and prevalence of cardiac, cerebrovascular, and peripheral vascular disease in multiple sclerosis

http://www.ncbi.nlm.nih.gov/pubmed/25533300

Abstract
BACKGROUND:
Findings regarding the prevalence of vascular comorbidities in multiple sclerosis (MS) are conflicting.

OBJECTIVE:
The objective of this review is to estimate the ...
Read more : MS and vascular problems associated | Views : 598 | Replies : 5


Maybe it is possible to protect the BBB

This is a recently published article about the BBB breakdown. It is still too early to know whether it is important, but I think it is worthy to have it around here.

http://www.ncbi.nlm.nih.gov/pubmed/25535736

Interleukin-34 Restores Blood-Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells.

Abstract
Interleukin-34 (IL-34) is a newly discovered cytokine as an additional ligand for colony stimulating factor-1 receptor (CSF1R), and its functions are expected ...
Read more : Maybe it is possible to protect the BBB | Views : 409 | Replies : 1


NPH

Read more : NPH | Views : 390 | Replies : 0


Looking Dr. Marian Simka's information

I have been diagnosed with MS for 30 years but it wasn't until 10 years ago I started having walking difficulties. After trying what pharmaceuticals have to offer, I am medication free and I strongly believe and can see a connection with Dr. Zamboni and Dr. Marian Simka with my symptoms. Does anyone know how to contact any of them? --Betsy
Read more : Looking Dr. Marian Simka's information | Views : 717 | Replies : 12


Propose for TED talk

Folks,

I am sure many of you are aware of TED talk. If some of you have not, I do suggest you listening to some of the topics on Biology, Health, Brain etc. The insight TED provides is just incredible. The other day, I was listening to this speaker who was explaining why sleep is essential (http://www.ted.com/talks/jeff_iliff_one ... ht_s_sleep) and some of the findings were simply an eye opener ...
Read more : Propose for TED talk | Views : 616 | Replies : 7


CCSVI: How RRMS becomes SPMS

The French Neurologist Jean-Martin Charcot, practicing at the Parisian la Pitié-Salpetrière hospital, first described Multiple Sclerosis (Sclérose en Plaques) in 1868. Among other things, he defined MS as a “rigidity disorder”. He thus set the tone in the Neurology profession of an unfortunate prejudice towards MS patients by claiming their “rigidity” symptoms were psychological in origin - signs of neurotic (usually female) hysteria. I now believe it is just this rigidity which is at the ...
Read more : CCSVI: How RRMS becomes SPMS | Views : 442 | Replies : 0


Sleep restriction impairs blood-brain barrier function

J Neurosci. 2014 Oct 29;34(44):14697-706. doi: 10.1523/JNEUROSCI.2111-14.2014.

Sleep restriction impairs blood-brain barrier function.

He J1, Hsuchou H1, He Y1, Kastin AJ1, Wang Y1, Pan W2.
n
Abstract
The blood-brain barrier (BBB) is a large regulatory and exchange interface between the brain and peripheral circulation. We propose that changes of the BBB contribute to many pathophysiological processes in the brain of subjects with chronic sleep restriction (CSR). To achieve CSR that mimics a common pattern of ...
Read more : Sleep restriction impairs blood-brain barrier function | Views : 392 | Replies : 2


 

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