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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Dr. Haskal at ISNVD 2014

from a slide picture that Joan put up on the CCSVI in MS facebook page
Clinical application led to early signal led to widespread dissemination in uncontrolled fashions led to medical tourism led to financial conflicts of interest led to polarizing (bidirectional) rhetoric led to mutual exaggerations led to extraordinary citizen and patient involvement

T1 and T2 steps were sidestepped

Anyone familiar with "T1 and T2 steps"? I am guessing that means research.
This is ...
Read more : Dr. Haskal at ISNVD 2014 | Views : 624 | Replies : 5


Catheter-Based, Forward-Looking, Real-Time, 3D Imaging

http://www.sciencedaily.com/releases/20 ... 100049.htm

Researchers have developed the technology for a catheter-based device that would provide forward-looking, real-time, three-dimensional imaging from inside the heart, coronary arteries and peripheral blood vessels.

"Our device will allow doctors to see the whole volume that is in front of them within a blood vessel," said F. Levent Degertekin, a professor in the George W. Woodruff School of Mechanical Engineering at the Georgia Institute of ...
Read more : Catheter-Based, Forward-Looking, Real-Time, 3D Imaging | Views : 336 | Replies : 0


Researchers urge further study of venous abnormalities

Researchers urge further study of venous abnormalities


UB researchers who authored one of neurology’s most cited papers in the past three years are calling for more investigation into how venous abnormalities in the neck might be involved in central nervous system

http://www.buffalo.edu/ubreporter/resea ... etail.html
Read more : Researchers urge further study of venous abnormalities | Views : 351 | Replies : 0


Stress matters to brain's white matter

Here is an interesting article in the LA Times that doesn't actually mention MS, let alone CCSVI, but it does mention cortisone, myelin, brain white matter, and oligodendrocytes:

http://www.latimes.com/science/sciencenow/la-sci-sn-white-matter-stress-20140211,0,7536685.story#axzz2t8CwkPUg

Basically the article seems to be saying (toward the end of the article) that stress and cortisone both trigger stem cells in the brain to become new myelin instead of new neurons.

The cell re-programs changes its fate, from wanting to become a neuron to wanting ...
Read more : Stress matters to brain's white matter | Views : 379 | Replies : 2


CCSVI in Meniere's Syndrome

http://www.isnvdconference.org/program/ ... -book.html
Presented at ISNVD 2014
CCSVI in Meniere’s Syndrome: Diagnosis and Treatment

A. Bruno M.D., L. Califano M.D., D. Mastrangelo° M.D., M. De Vizia M.D. ° B. Bernardo° M.D. Dept of Vascular and Endovascular Surgery -GEPOS CLINIC Telese Terme (BN) ITALY - Dept of Audiology and Phoniatrics, G. Rummo Hospital Benevento ITALY

Background: Menière’s Syndrome described in 1861 by Prospero Menière. The disease is characterized by the ...
Read more : CCSVI in Meniere's Syndrome | Views : 586 | Replies : 2


Clive Beggs at ISNVD 2014

http://www.isnvdconference.org/program/ ... -book.html
Venous Hemodynamics in Neurologic Disorders

Clive Beggs, Ph.D. (Centre for Infection Control and Biophysics, University of Bradford, Bradford, UK)

Abstract There is increasing evidence that the cerebral veins and sinuses play an important role in regulating fluids in the intracranial space . There is evidence that venous anomalies may contribute to the pathophysiology of several neurological conditions, including multiple sclerosis (MS) , leukoaraiosis [5, ...
Read more : Clive Beggs at ISNVD 2014 | Views : 803 | Replies : 11


the CCSVI "cult" following includes the doctors???

http://www.isnvdconference.org/program/ ... -book.html
Intervention Studies 2014 B. Therapy Trials Need to Wait. The Landscape has Changed

Kottil W. Rammohan, M.D.

Background: Numerous open label and few blinded studies have been reported on the “liberation” therapy since the original description of the disorder by Dr. Paolo Zamboni in 2008. Although most of these trials report no benefit for this endovascular intervention, Over 30,000 patients with various types and stages of ...
Read more : the CCSVI "cult" following includes the doctors??? | Views : 383 | Replies : 2


How should a ccsvi trial differ from an MS drug trial?

http://www.isnvdconference.org/program/ ... -book.html
Designing an Endovascular Trial – What Elements are Essential and Why CCSVI Trials Might Differ from Disease Modifying Trials?

Kottil W. Rammohan, M.D. Background: “Liberation” of CCSVI has been associated with reports of variable efficacy both in the short as well as in the long term. Most claims of efficacy has however not withstood the scientific rigors of double-blind trials. Many of these trials have suffered ...
Read more : How should a ccsvi trial differ from an MS drug trial? | Views : 323 | Replies : 2


Foundational research is being done

http://www.buffalo.edu/news/releases/2014/02/0050.html
Zivadinov and his colleagues published a paper on the prevalence of these abnormalities in multiple sclerosis (MS) patients in 2011. The paper is one of the top ten articles in neurology and the second most cited paper in neurology since its publication, according to Neuropenews, the news blog of the European Federation of Neurological Societies and the European Neurological Society.

Think of the citations.
The research being done ...
Read more : Foundational research is being done | Views : 304 | Replies : 0


healthy controls are not healthy controls

http://www.isnvdconference.org/program.html
Inverse Relationship between Internal Jugular Vein Narrowing and Increased Brain Volumes in Healthy Individuals – Podium Presentation - #42

Chris Magnano, M.S., 1,2, Pavel Belov1, Jacqueline Krawiecki1, Steven Grisafi1, Jesper Hagemeier1, M.S., Clive, B. Beggs, Ph.D. 3, Robert Zivadinov 1,2, M.D., Ph.D.

Background: Brain volume reduction (atrophy) and internal jugular vein (IJV) narrowing have been implicated in central nervous system pathologies, but have never previously been linked.

Objectives: ...
Read more : healthy controls are not healthy controls | Views : 283 | Replies : 2


 

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