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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

new research: short bursts of exercise improve MS fatigue ... 4.abstract
Pragmatic intervention for increasing self-directed exercise behaviour and improving important health outcomes in people with multiple sclerosis: a randomised controlled trial


Background: Exercise programmes that can demonstrate evidence of long-lasting clinical effectiveness are needed for people with multiple sclerosis (PwMS).

Objective: The objective of this study was to assess the effects of a practically implemented exercise programme on self-directed exercise behaviour and important health outcomes ...
Read more : new research: short bursts of exercise improve MS fatigue | Views : 521 | Replies : 2

Ccsvi in Europe

Hi everyone I'm looking for some advice in relation to ccsvi. I'm looking to get the Doppler test I live in Ireland yet I cannot find anywhere in Ireland that will test me. Does anyone know if the clinic in Scotland is still carrying out the procedure. I am aware of the treatment in Poland it's just I would like to know if I needed the procedure before I head over to Poland. I'm very ...
Read more : Ccsvi in Europe | Views : 477 | Replies : 0

ISNVD lectures available

Carol Schumacher, on Facebook:
We have been authorized by ISNVD to share the login and password given to participants of the conference. You can access the entire program for free. Please share freely especially with the medical professionals you work with.......... On behalf of the ISNVD Course Directors, Drs. Michael Dake, Robert Zivadinov, E. Mark Haacke, Ziv Haskal and Chih-Ping Chung, we would like to thank you for your participation in the 4th Annual ...
Read more : ISNVD lectures available | Views : 375 | Replies : 0

study shows cerebral venous outflow is abnormal in MS
AJNR Am J Neuroradiol. 2014 Mar 7.

A Sonographic Quantitative Cutoff Value of Cerebral Venous Outflow in Neurologic Diseases: A Blinded Study of 115 Subjects.

Monti L1, Menci E, Piu P, Leonini S, Arrigucci U, Bellini M, Zandonella A, Galluzzi P, Casasco A.



The autonomic nervous system maintains constant cerebral venous blood outflow in changing positions. Alterations in cerebral autoregulation ...
Read more : study shows cerebral venous outflow is abnormal in MS | Views : 1363 | Replies : 13


I noticed back when I was in college (pre MS days), I would feel an odd sensation whenever I got a haircut. Namely, when they used the clippers to shave the back of my neck, I would feel, well, it's hard to describe, something like a tickle or an itch under the skin. It only happened on the right side. It wasn't real pronounced, but enough that I noticed. I would say it was somewhat ...
Read more : questions | Views : 631 | Replies : 3

CCSVI whilst still CIS?

Hi all,

Many years ago (we are talking 80s and 90s) a treatment here in Spain became popular amongst MS patients. It was known as CTOS and involved the cutting if part of the scalene muscle to ease pressure in the jugular vein.

I have located the doctor and had the basic tests done. Using Doppler he found the right juglar vein obstructed as he followed it up towards the skull. When measuring blood flow ...
Read more : CCSVI whilst still CIS? | Views : 555 | Replies : 2

Microbleeds in the MS brain

Canadian microbiologists look at the iron around MS lesions, and link it to the vasculature and "chronic extravasation of hemoglobin", or microbleeds causing oxidative stress in the brain. This is what Dr. Zamboni proposed in 2006 in his "Big Idea" paper on the similarities of MS and venous disease. More researchers connecting MS lesions to the vasculature.

Although iron is known to be essential for the normal development and health of the central nervous system, ...
Read more : Microbleeds in the MS brain | Views : 972 | Replies : 7


Robert Zivadinov, MD, PhD, says new research may reveal how extracranial venous abnormalities contribute to various diseases as well as aging.
UB Researchers Urge Broad Study of Venous Abnormalities
Published February 27, 2014

Although their oft-cited prior study found no causal relationship between venous abnormalities in the neck and multiple sclerosis (MS), University at Buffalo neurological researchers are strongly advocating more investigation.

“We have developed a substantial body of work looking at these abnormalities in ...

KIR4.1 antibodies and CCSVI

The American Academy of Neurology will be meeting in Philadelphia from April 26-May 3. In advance of this meeting, some press releases are being sent out. Apparently, the BIG NEWS in MS research is KIR4.1 antibodies are present in about half of the plasma samples from patients with a pre-clinical diagnosis of MS patients, and this could be a diagnostic and treatment target. According to research by the Technical University in Munich-

The researchers found ...
Read more : KIR4.1 antibodies and CCSVI | Views : 1649 | Replies : 16

Dr. Zamboni at ISNVD 2014 on valves

from a slide from a presentation by Dr. Zamboni at ISNVD 2014, posted by Joan over at CCSVI Alliance facebook page
1. In healthy subjects, the IJV valve leaflets are ALWAYS mobile and open in up-right.
2. 62% of healthy controls with valve absence at least of one side suggests a progressive LOSS OF PHYLOGENETIC IMPORTANCE of such apparatus
4. The ATRIAL CONTRACTION induces ...
Read more : Dr. Zamboni at ISNVD 2014 on valves | Views : 654 | Replies : 1


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