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A board to discuss future MS therapies in early stage (Phase I or II) trials.

A new drug for treating M.S developed by cambridge university research read the site more information

Positive phase2 results reported for RPC1063 in relapsing MS

Receptos, Inc. announced that the Phase 2 portion of the RADIANCE trial of its selective S1P1 receptor modulator, RPC1063, in relapsing multiple sclerosis (RMS) met the primary endpoint, reduction in MRI brain lesion activity. The overall safety profile of RPC1063 was consistent with the results of prior trials, and continues to support the differentiation of the drug candidate against other oral agents for treatment of RMS on the market or in clinical development..... Read More ...
Read more : Positive phase2 results reported for RPC1063 in relapsing MS | Views : 977 | Replies : 0

The influence of cannabinoids on neurodegeneration (mice)

another recent research study on cannabinoids. Nothing MS specific, but the usual suspects are all there.
In an increasingly ageing population, the incidence of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Huntington's disease are rising. While the aetiologies of these disorders are different, a number of common mechanisms that underlie their neurodegenerative components have been elucidated; namely neuroinflammation, excitotoxicity, mitochondrial dysfunction and reduced trophic support. Current therapies focus on treatment of ...
Read more : The influence of cannabinoids on neurodegeneration (mice) | Views : 878 | Replies : 0


I stopped Copaxone for 4 mos to try Tecifedera but got worse, now back on Copaxone.
Read more : Tecfidera | Views : 1407 | Replies : 3

Aubagio... any experience?

I have agreed with my neuro to start the aubagio treatment. I have been dmd free for 8 months. Previously on avonex. Turns out that I do need meds because diet, nutrition and gluten free did not keep me in remission. I have an mri appointment and soon to start aubagio. I guess what I am looking for is how this drug is working. My neuro tells me that it is the most tolerated. Do ...
Read more : Aubagio... any experience? | Views : 8024 | Replies : 29

Wanting off Avonex

I'm new here. I was diagnosed in September of last year. I am currently taking Avonex injections, Zoloft, Percocet, Dilotid, Ativan, and I most recently Valium and Flexeril. I feel like I am singlehandedly keeping the drug companies in business! :wink:

A little background on me: I'm 28, mother of 4 (8,6,3,2yrs) wife of 10 years, and we live in a small town in New England. ...
Read more : Wanting off Avonex | Views : 1093 | Replies : 5

Chemical compound shows promise as treatment for autoimmune ... or-ms.html

Researchers at Oregon State University have identified a chemical compound that could be used to more safely treat patients with autoimmune diseases. After testing thousands of compounds, scientists uncovered 10-CI-BBQ, which binds to a T-cell protein, and together they pass into the nucleus to shut down the immune response by changing the cells into regulatory T cells, according the study published in PLoS ONE. "f this ...
Read more : Chemical compound shows promise as treatment for autoimmune | Views : 1399 | Replies : 3

Testosterone and Neuroprotection

An interesting article on Pub Med today re: testosterone.

Neuroprotective Effects of Testosterone full article available.

Highlights of the article:

Ten men with MS were observed by MRI before and after testosterone treatment.

VBM demonstrated an arrest of gray matter atrophy as the result of treatment.

VBM demonstrated an increase of cortical gray matter as the result of treatment.

(VBM=voxel-based morphometry, a sophisticated, objective whole-brain analysis technique)

The discussion section had some interesting observations too ...
Read more : Testosterone and Neuroprotection | Views : 1324 | Replies : 4

Tisch MS Research Center of New York receives green light

At last!

Please look at this:
and this:
(Thanks Marc for your post)

Good luck to Dr. Sadiq, his entire team and all the patients.
Read more : Tisch MS Research Center of New York receives green light | Views : 1014 | Replies : 0

Stem Cell

has anyone tried stem cell therapy for MS and if you did can you elaborate more on it?
Read more : Stem Cell | Views : 2219 | Replies : 7


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