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A board to discuss future MS therapies in early stage (Phase I or II) trials.

drug study results

In this video from TED Dr. Goldacre expalins why it is hard to get the real results from these studies.

http://articles.mercola.com/sites/artic ... n=20130213
Read more : drug study results | Views : 822 | Replies : 3


Has anyone here had BOTOX injections in the bladder ?

a uro-neurologist has offered me this treatment option of having BOTOX injections in the bladder to improve bladder incontinence symptoms,
he said it improves MS patients urgency, frequency and control of their bladder,
you are under a local anaesthetic for 45 minutes during the injections, and the effects last 6-12 months before requiring further injections,

this 'trial' seems promising and as i have this option for treatment am very tempted to go ahead with the ...
Read more : Has anyone here had BOTOX injections in the bladder ? | Views : 2562 | Replies : 20


Neurosteroids

It is older story, but might merit more attention as hormon levels can be adjusted even without a new drug:

"Studies in EAE mice showed reduced neurosteroid levels in their brains. Intraperitoneal
injections of allopregnanolone in mice shortly after induction of EAE led to improvements in several
markers of disease, relative to sham-treated animals.

These included:
Preserved myelin in the spinal cord
Reduced reactivity in immune cells
Lower immunoreactive cell counts in the spinal cord ...
Read more : Neurosteroids | Views : 754 | Replies : 0


Amiloride

Anyone tried Amiloride? Any experience with i? As it is already a cheap prescription drug with safe track record and with great potential for progressive patients, I would have assumed that some doctors might have prescribed it or someone tried it.

Amiloride study in Multiple Sclerosis wins national award

This week the Multiple Sclerosis (MS) research team at University of Oxford was awarded the prestigious MS Research Project of the Year award. The award was ...
Read more : Amiloride | Views : 3004 | Replies : 15


MSRV Retrovirus, phase 2

Hello everybody :smile:

I am involved in the following study, described hereafter.

Mister Hervé Perron, who found the retrovirus, gave more details here : http://www.forseps.org/t1921-reponses-sur-le-retrovirus (in French), and you can follow my experience regarding this test here : http://www.forseps.org/t1920-fred1208-geneve (in French).

Source http://www.bioworld.com :

Spun out in 2006 from ...
Read more : MSRV Retrovirus, phase 2 | Views : 4785 | Replies : 27


Phenytoin

Not sure if this has been posted elsewhere.

http://www.youtube.com/watch?v=Y3s4mOTc ... ture=share
Read more : Phenytoin | Views : 894 | Replies : 0




BG 12

Hey Dig, long time. What is your latest take on BG12? Is this really fumeric acid? All my Neuros seem to think its the Holy Grail but if we can just do it ourselves why would anyone sign on for a high dollar Med? Rituxan coming up hard and fast!
Lars
Read more : BG 12 | Views : 1676 | Replies : 8


Wow-too good to be true? Nanotechnology- Immune therapy

http://www.eurekalert.org/pub_releases/ ... 111312.php


I guess this is just getting picked up by national media.

Looks like phase 2 is only recruiting newly diagnosed:

"A phase 2 trial will explore how effective the therapy is in newly diagnosed patients, and will expand the sample size for further evaluation."

trisca wrote:
And if it is a real breakthrough and solves it, how long before all the studies are done and we ...
Read more : Wow-too good to be true? Nanotechnology- Immune therapy | Views : 1526 | Replies : 1


Nuron closing in on new treatment for relapsing MS

Image

Nuron Biotech Inc. said Tuesday it has completed enrollment of 500 patients for a pivotal phase-III study evaluating the safety and effectiveness of the company’s experimental multiple sclerosis treatment.

Phase-III studies are typically the last hurdle a drug developer must clear before seeking approval for a new drug candidate.

Nuron, an Exton, Pa., specialty biologics and vaccines company, is developing NU100 to treat relapsing remitting multiple sclerosis.

Shankar Musunuri, the company’s founder and CEO, ...
Read more : Nuron closing in on new treatment for relapsing MS | Views : 1016 | Replies : 1


 

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