This Is MS Multiple Sclerosis Community: Knowledge & Support

**Posted:** Fri Sep 10, 2010 11:30 am

Sounds good so far.

<shortened url>

**Posted:** Sun Sep 05, 2010 3:24 pm

How scary is this scenario?

Quote:

Most Neurologists Plan to Prescribe Oral Multiple Sclerosis Drugs, but Will Proceed with Caution

In a study published this week by Majestic Research, almost 60% of neurologists expressed unaided concern about the side effects/safety of oral MS therapies in development, including NVS’s Gilenia and MRK/EMD Serono’s oral cladribine. Despite their concerns, the vast majority of neurologists expect to prescribe these drugs if they are approved, as the new oral MS ...

**Posted:** Wed Aug 25, 2010 10:24 pm

Hi everyone
I am looking for a method for the drug rapamycin,I am currently experiencing fronting. Mobile phase:MeOH\H2O dissolving in MeCN tried flow rates 0.5-1ml/min also tried using buffer with no success.any ideas on what I can do to move foward?

**Posted:** Mon Jul 12, 2010 1:12 pm

http://www.ncbi.nlm.nih.gov/pubmed/20599429

--Frank

**Posted:** Tue Jul 06, 2010 8:30 pm

Epstein–Barr virus in bone marrow of rheumatoid arthritis patients predicts response to rituximab treatment

Results. Before RTX treatment, EBV was identified in 15 out of 35 patients (EBV-positive group), of which 4 expressed parvovirus. Parvovirus was further detected in eight patients (parvo-positive group). Twelve patients were negative for the analysed viruses. Following RTX, EBV was cleared, whereas parvovirus was unaffected. Eighteen patients were responders, of which 12 were EBV positive. The decrease in the DAS-28 ...

**Posted:** Tue Jul 06, 2010 12:50 pm

**Posted:** Mon Jun 28, 2010 6:44 pm

Is anyone on this? How is it working for you? My neuro mentioned having me on it after the CCSVI treatment (on July 20 Yayyyyyyyyyy!!!!!!!!!!!!)

He said he might be able to get it for me on "compassionate grounds" because I have developed antibodies/become allegic to/ saw no positive results from the CRABs

Funny how they can fastrack for a drug, but not for CCSVI :roll:

**Posted:** Thu Jun 10, 2010 6:43 pm

I know, I know, the news has already been posted in a couple of other threads, but I just wanted to highlight one thing that I think is a great idea (I think the FDA panel stole it from me, I'm sure they're all dedicated readers of the thisisms forums)

Quote:

...panelists questioned whether an even lower dose might be safer while still benefiting patients.

Panelists voted 20-5 that Novartis should be required to study a ...

**Posted:** Mon May 24, 2010 2:30 pm

Daclizumab trial for relapsing-remitting MS begins

ZenapaxActive Comparator Study Designed to Examine the Safety and Efficacy of Daclizumab Formulated for Monthly Subcutaneous Dosing.

Biogen Idec and Abbott today announced enrollment of the first patient in a global Phase III study evaluating the efficacy and safety of daclizumab compared to interferon beta-1a (Avonex(R)) in patients with relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS).

The trial, called DECIDE, will investigate a ...

**Posted:** Thu Apr 29, 2010 3:41 pm

I have been on Ampyra for a little over 2 weeks...so far my spasticity has been nearly diminished and do notice that i am walking 4 seconds faster on the 25 foot walk (neuro- office)...do not be afraid if it initially causes some pain or even old symptoms appear...for me they did and then they are slowly going away...think it is also due to the fact that i have a wicked viral thing going on...and ...

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