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In an increasingly ageing population, the incidence of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Huntington's disease are rising. While the aetiologies of these disorders are different, a number of common mechanisms that underlie their neurodegenerative components have been elucidated; namely neuroinflammation, excitotoxicity, mitochondrial dysfunction and reduced trophic support. Current therapies focus on treatment of ...
Ten men with MS were observed by MRI before and after testosterone treatment.
VBM demonstrated an arrest of gray matter atrophy as the result of treatment.
VBM demonstrated an increase of cortical gray matter as the result of treatment.
(VBM=voxel-based morphometry, a sophisticated, objective whole-brain analysis technique)
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