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A board to discuss future MS therapies in early stage (Phase I or II) trials.


Some trial results for an oral drug - Laquimod

The results are to be presented during the ACTRIMS / ECTRIMS conference which takes place in the latter half of this week. No doubt other trial results will be presented - results for Tovaxin and NeuroVax are being presented.

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Drug for control over emotions

The approval for a drug for MS sufferers who can't control their emotions has been delayed - not surprising that we can't control our emotions given that the drugs they create are either ineffective, kill, or are subject to delays!
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The following research paper suggests that cannaboids are useful in relation to neuro-degenerative / inflammatory diseases.

The UK are funding some large scale trials into cannaboids as there is some evidence that they may ahve a neuro-protective effect -

Clinical Trials of cannabinoids as neuroprotective agents in MS
Professor John Zajicek, from the Peninsula Medical School in Plymouth, outlined the reasons for believing that some cannabinoids (chemicals derived ...
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Just incase we missed something

Clinical Trials In Multiple Sclerosis 2005:

Sorry having a hard time entering this link so try getting there through google. Second one down on google link

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Read more : Just incase we missed something | Views : 1583 | Replies : 2

Drug for ALS

This is an early trial for a drug for ALS but could also be of benefit to MS.

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Another drugs comany involved in MS treatments

Another drugs company expanding into MS treatments

Read more : Another drugs comany involved in MS treatments | Views : 1262 | Replies : 0

vasoactive intestinal peptide

Another t-reg experimental therapy...

Spanish scientists develop a cellular therapy for rheumatoid arthritis and multiple sclerosis

2005-09-09 -- A research team at the Institute of Parasitology and Biomedicine of the Spanish National Research Council (CSIC), in Grenade, has successfully developed in mice a cellular therapy for two major autoimmune diseases: rheumatoid arthritis and multiple sclerosis. The scientists succeeded, in both experimental models, in making the symptoms disappear and inducing a reversion of the degenerative process. ...
Read more : vasoactive intestinal peptide | Views : 1568 | Replies : 2


Dear all,

Not sure if this article has been posted before- it's about Neurovax and the experience of one triallist. Looks promising (like Tovaxin) - but don't they all! Probably a few years before it reaches thr market (if the trials are successful).


PS Apologies Dignan had already posted on this earlier. It was on the NZ MS site today so I assumed it was new news!
Read more : Neurovax | Views : 1660 | Replies : 0

Riluzole completed Phase I for PPMS

The Accelerated Cure project mentioned this small Phase I trial in their news section today. Riluzole is a drug for ALS. It's always good news when they test a drug for PPMS.

Glutamate inhibition in MS: the neuroprotective properties of riluzole

J Neurol Sci. 2005 Jun 15;233(1-2):113-5. Epub 2005 Apr 20.

Killestein J, Kalkers NF, Polman CH.
Department of Neurology, VU Medical Centre, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. ...
Read more : Riluzole completed Phase I for PPMS | Views : 1486 | Replies : 1

Cannabinor in Phase I trials

I guess I jumped the gun on my pipeline list a bit as I already had this in Phase I.

Pharmos Initiates Phase I Trial of CB2-Selective Drug Candidate Cannabinor

Sept. 6 -- PRNewswire-FirstCall -- Pharmos Corporation announced today that it has initiated a Phase I trial with cannabinor, a CB2-selective synthetic cannabinoid drug candidate. The study will assess the safety, tolerability and pharmacokinetics of cannabinor in healthy volunteers.

The trial will enroll up to ...
Read more : Cannabinor in Phase I trials | Views : 1288 | Replies : 0


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