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A board to discuss future MS therapies in early stage (Phase I or II) trials.

Another drugs comany involved in MS treatments

Another drugs company expanding into MS treatments

Read more : Another drugs comany involved in MS treatments | Views : 1364 | Replies : 0

vasoactive intestinal peptide

Another t-reg experimental therapy...

Spanish scientists develop a cellular therapy for rheumatoid arthritis and multiple sclerosis

2005-09-09 -- A research team at the Institute of Parasitology and Biomedicine of the Spanish National Research Council (CSIC), in Grenade, has successfully developed in mice a cellular therapy for two major autoimmune diseases: rheumatoid arthritis and multiple sclerosis. The scientists succeeded, in both experimental models, in making the symptoms disappear and inducing a reversion of the degenerative process. ...
Read more : vasoactive intestinal peptide | Views : 1642 | Replies : 2


Dear all,

Not sure if this article has been posted before- it's about Neurovax and the experience of one triallist. Looks promising (like Tovaxin) - but don't they all! Probably a few years before it reaches thr market (if the trials are successful).


PS Apologies Dignan had already posted on this earlier. It was on the NZ MS site today so I assumed it was new news!
Read more : Neurovax | Views : 1775 | Replies : 0

Riluzole completed Phase I for PPMS

The Accelerated Cure project mentioned this small Phase I trial in their news section today. Riluzole is a drug for ALS. It's always good news when they test a drug for PPMS.

Glutamate inhibition in MS: the neuroprotective properties of riluzole

J Neurol Sci. 2005 Jun 15;233(1-2):113-5. Epub 2005 Apr 20.

Killestein J, Kalkers NF, Polman CH.
Department of Neurology, VU Medical Centre, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. ...
Read more : Riluzole completed Phase I for PPMS | Views : 1643 | Replies : 1

Cannabinor in Phase I trials

I guess I jumped the gun on my pipeline list a bit as I already had this in Phase I.

Pharmos Initiates Phase I Trial of CB2-Selective Drug Candidate Cannabinor

Sept. 6 -- PRNewswire-FirstCall -- Pharmos Corporation announced today that it has initiated a Phase I trial with cannabinor, a CB2-selective synthetic cannabinoid drug candidate. The study will assess the safety, tolerability and pharmacokinetics of cannabinor in healthy volunteers.

The trial will enroll up to ...
Read more : Cannabinor in Phase I trials | Views : 1400 | Replies : 0

Article about MN-166 Phase II trial

This is one that's been talked about before, but here is a new article.

Doctors to Test Stroke Drug for MS

09-02-05 - A medication currently available in Southeast Asia to treat asthma and vascular disorders in the brain is now undergoing clinical testing as a possible therapy for multiple sclerosis. The drug is known as Ketas® (ibudilast) in Japan and Korea. But it uses a code name, MN-166, in its current clinical scrutiny as ...
Read more : Article about MN-166 Phase II trial | Views : 1614 | Replies : 0

Anecdotal reports on Neurovax

This could just be the Immune Response Corp's marketing department getting revved up, buy I'll try not to think too cynically about this and just be happy that it seems to really help some people based on early-stage clinical trial reports.

MS Vaccine Shows Promise

Aug 29, 2005 - Some exciting news on the horizon for multiple sclerosis patients. Scientists are testing a vaccine that seems to halt the progression of the disease. I t's ...
Read more : Anecdotal reports on Neurovax | Views : 1562 | Replies : 0

Tovaxin News

David McWilliams, CEO of PharmaFrontiers Corp, recently gave an interview with on August 25, 2005. The mp3 audio file of the interview can be found here. While the interview is targeted towards investors and not a scientific audience, there is still some very encouraging news none-the-less. During the interview, David McWilliams indicates that they are obtaining a 90% reduction in relapses! In addition, he states that 40% of their patients have improved physically with ...
Read more : Tovaxin News | Views : 2413 | Replies : 1

High dose Betaseron trial

I have a hard time getting too excited about this...

Largest Ever MS Trial Completes Patient Enrollment

08-26-05 -- What's being described as the largest double-blind, randomized clinical trial for multiple sclerosis (MS) has completed its patient enrollment phase, according to the trial's sponsor, Berlin-based Schering AG. The trial will involve 2100 patients diagnosed with relapsing-remitting MS at more than 200 study centers located in 26 countries. It's aimed at testing the safety and effectiveness ...
Read more : High dose Betaseron trial | Views : 1751 | Replies : 2

Immunoadsorption (is this the same as plasma exchange?)

This study is promising.

Eur J Clin Invest. 2005 Aug;35(8):523-30.

Immunoadsorption patients with multiple sclerosis: an open-label pilot study.

Moldenhauer A, Haas J, Wascher C, Derfuss T, Hoffmann KT, Kiesewetter H, Salama A. -- Charite--Universitatsmedizin Berlin, Germany.

BACKGROUND: Immunoadsorption (IA) is occasionally applied in patients with acute relapses of multiple sclerosis (MS). This pilot study was undertaken to determine whether IA might help in secondary progressive and relapsing-remitting multiple ...
Read more : Immunoadsorption (is this the same as plasma exchange?) | Views : 1388 | Replies : 0


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