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Good news for MBP8298 Phase II/III trial...



Data Safety Monitoring Board gives positive review for BioMS Medical's pivotal MS trial

October 27 - CNW - BioMS Medical Corp., a leading developer in the treatment of multiple sclerosis (MS), announced that following the second meeting of its independent Data Safety Monitoring Board (DSMB), the Company has received a recommendation to continue its pivotal phase II/III clinical trial for MBP8298 for the treatment of secondary progressive multiple ...

This is my first post and I don't really have a clue what I am doing! I came across this "lead-in" article on the "news for the day", i.e., current, New England Journal website. It costs $29.95 to read the entire article and I really don't want to make the investment. Perhaps some of you know what this means:

Progressive Multifocal Leukoencephalopathy, Natalizumab, and Multiple Sclerosis

To the Editor: According to the established definition of ...

http://c.moreover.com/click/here.pl?j412355639&w=464753

Rituximab (rituxan) is in Phase ii trials (Biogen is the drugs company behind rituxan).

The following research paper suggests it has benefits - it affects B cells (rather than the usual T cells)

Bromley

http://www.msif.org/en/research/researc ... tabil.html

http://c.moreover.com/click/here.pl?j403390149&w=464753

Antisense Therapeutics were trialling an oral drug which targeted the same protein as Tysabri. The company stopped the trial following the Tysabri fiasco. The company has applied to restart the trial (may need to add to Dignan's list of approval given).


http://www.antisense.com.au/dl/415.pdf

New NeuroVax Data from the European MS Meeting


http://biz.yahoo.com/bw/051003/35350.html?.v=1



Dunmann.

http://biz.yahoo.com/bw/051003/35233.html?.v=1

http://c.moreover.com/click/here.pl?j399628250&w=464753


And another article which also refers to Mylinax (sp?). Still looking at 2008 or 2009 before an oral therapy is available.

http://c.moreover.com/click/here.pl?j399635862&w=464753

I have no idea what Padma28 is but it seems to have some benefit for chronic progressive ms sufferers.


http://www.ever.ch/padma28ms.htm


PS I found some more information - it's a Tibetan medicine.

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It seems to consist of a vast range of ingredients - as our nutrition expert Melody might translate for us.