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Unknown component found in MS CSF

A previously unknown component has been identified in the CSF (Cerebrospinal fluid) of MS patients.

This component has been found by spectrography, and it is not known by now. The researchers only know that it presents a peak around the 523.0 m/z (mass to charge ratio)

This is the original article. Along with the unknown component, also glutamate and some cholines.

An integrated metabolomics approach for the research ...
Read more : Unknown component found in MS CSF | Views : 158 | Replies : 0

Early research shows results for ‘vaccine’

In April 2010, sipuleucel-T (Provenge) became the first dendritic cell vaccine in cancer treatment to be approved by the US Food and Drug Administration (FDA), and the agent is now used in the treatment of metastatic castration-resistant prostate cancer. Insights gleaned from this research are now being applied in the study of a potential vaccine for multiple sclerosis (MS) treatment and prevention.

“We discovered DC-ASGPR, one of the receptors expressed on human dendritic cells, has ...
Read more : Early research shows results for ‘vaccine’ | Views : 183 | Replies : 0

Uric acid correlated with MS disease activity

In a study published in the journal Clinical Chemistry and Laboratory Medicine, investigators Moccia et al identified uric acid as a potential biomarker in the progression of multiple sclerosis-related disability..... Read More -
Read more : Uric acid correlated with MS disease activity | Views : 178 | Replies : 0


Given the recent hysteria in the news about vaccines it occurred to me that I should probably spend some time informing myself of which vaccines are appropriate for me to have. The NMSS gives very conflicting recommendations for vaccinations. My neuro told me to stay away from all live vaccines but that others were safe. The NMSS says the same and then goes on to recommend multiple live vaccinations to PwMS including MMR (confusing much?!): ...
Read more : vaccinations | Views : 136 | Replies : 0

MSRV GNbAC1 from GeNeuro

From their newsletter: (This is about therapy for MSRV or MS retrovirus.)

GNbAC1 has successfully completed Phase I in healthy volunteers showing that GNbAC1 is very well tolerated. GNbAC1 has also successfully completed Phase IIa last year, demonstrating an optimal safety profile and encouraging signs of efficacy on a first mall cohort of MS patients.

Information about the clinical trials are posted on,
identifiers NCT01639300 & NCT01699555.

A ...
Read more : MSRV GNbAC1 from GeNeuro | Views : 216 | Replies : 0

Scientists identify drug that could block MS

I saw this today and it really does seem like positive progress - whether in time for us, I am not sure ... hU.twitter

We can but hope! :-D

Read more : Scientists identify drug that could block MS | Views : 333 | Replies : 2

Cerebral circulation time in MS is double that of normals

New, blinded research shows cerebral circulation in pwMS takes twice as long as in normals, and this slowed blood flow does not correlate with EDSS or disability, or lesions and inflammation.

full paper in pdf form ... tation=PDF

The present study reported a significant CCT (cerebral circulation time) increase in MS patients compared to control subjects, indicating a consistent condition of cerebral hypoperfusion. Increase of CCT, and the ...
Read more : Cerebral circulation time in MS is double that of normals | Views : 296 | Replies : 3

Any thoughts...

Hi all,
Has anyone have any thoughts on the following...

I have been diagnosed 15 years, tried all sorts of things and consider myself to be fairly knowledgeable on many subjects related to MS. My most problematic symptom is gait/leg mobility, I can walk, slowly, for about 1/2 mile before things get too much of an effort and my legs stiffen so much that I need to stop - muscle fatigue plays a big part ...
Read more : Any thoughts... | Views : 229 | Replies : 1

New treatment for MS fatigue suggested

The Multiple Sclerosis Journal has published the results of a study by researchers from Israel who measured the effect of vitamin D analogue, Alfacalcidol, on MS-related fatigue.<br><br>

Fatigue is one of the most common and disabling symptoms of multiple sclerosis, occurring in up to 90 per cent of people with MS.... Read more -
Read more : New treatment for MS fatigue suggested | Views : 294 | Replies : 0

Research breathes new life into MS viral theory

Research breathes new life into theory supporting possible viral etiology of multiple sclerosis

Several clusters of multiple sclerosis cases have been identified around the world, some of which have occurred in association with exposure to infectious agents, while others have suggested an influence of environmental toxins, such as heavy metals.

Although MS is likely a result of multifactorial influences, there is some evidence that viruses play a role in the disease. For example, in the ...
Read more : Research breathes new life into MS viral theory | Views : 305 | Replies : 1


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