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Visual system as a predictor of change from CIS to MS

Evaluation of visual structural and functional factors that predict the development of multiple sclerosis in clinically isolated syndrome patients.

Perez-Rico C, Ayuso-Peralta L, Rubio-Pérez L, Roldán-Díaz I, Arévalo-Serrano J, Jiménez Jurado D, Blanco R.

Abstract

PURPOSE. To evaluate visual pathway structure and function in patients with clinical isolated syndrome (CIS) using spectral domain optical coherence tomography (OCT) and multifocal visual evoked potentials (mfVEP), predicting CIS conversion to clinically definite multiple sclerosis (MS).

METHODS. This observational, ...
Read more : Visual system as a predictor of change from CIS to MS | Views : 150 | Replies : 0


MS researchers find role for working memory in cognitive....

MS researchers find role for working memory in cognitive reserve

Kessler Foundation scientists have shown that working memory may be an underlying mechanism of cognitive reserve in multiple sclerosis (MS).

This finding informs the relationships between working memory, intellectual enrichment (the proxy measure for cognitive reserve) and long-term memory in this population..... Read More - http://www.ms-uk.org/cognition
Read more : MS researchers find role for working memory in cognitive.... | Views : 134 | Replies : 0


New Website to Review Disabled Accessibility

Hi:

I'm Nancy (diagnosed RRMS in 2008). After a series of relapses became dependent on a walker and scooter.

I recently launched a new site that enables contributors to review disabled accessibility of the places they go.

http://www.disabledonthego.com

Please come, join the community and post reviews. Your participation would help everyone in the MS community who uses mobility assistance aids (and other disabled persons as well)!

Nancy@disabledonthego.com
Read more : New Website to Review Disabled Accessibility | Views : 149 | Replies : 0


Could Dock3 protect against demyelination?

Dock3 protects myelin in the cuprizone model for demyelination.

Namekata K, Kimura A, Harada C, Yoshida H, Matsumoto Y, Harada T.

Abstract

Dedicator of cytokinesis 3 (Dock3) belongs to an atypical family of the guanine nucleotide exchange factors. It is predominantly expressed in the neural tissues and causes cellular morphological changes by activating the small GTPase Rac1.

We previously reported that Dock3 overexpression protects retinal ganglion cells from excitotoxic cell death. Oligodendrocytes are the myelinating ...
Read more : Could Dock3 protect against demyelination? | Views : 224 | Replies : 1


Body aches

I am fairly new to ms only being diagnosed in May this year and for the last month have been waking up with body aches all over in particular my legs. Most days lately I've been sleeping for a good 12 hrs a day and after only being awake a couple of hours I feel the need to go back to sleep. I just feel awful every day, tired aching and kind of weak. Has ...
Read more : Body aches | Views : 256 | Replies : 8


Comorbidities appear more prevalent in people with MS

While multiple sclerosis is most typically associated with progressively declining physical ability, multiple sclerosis patients are often times affected by a number of physical and mental health comorbidities in addition to their worsening physical ability. This observation was highlighted by a group of researchers in Scotland led by Drs. Robert J. Simpson and Stewart W. Mercer of the University of Glasgow...... Read More - http://www.ms-uk.org/qol
Read more : Comorbidities appear more prevalent in people with MS | Views : 217 | Replies : 0


The clincial meaning of 'Walking Speed'

The Clinical Meaning of Walking Speed as Measured by the Timed 25-Foot Walk in Patients With Multiple Sclerosis.

Cohen JA, Krishnan AV, Goodman AD, Potts J, Wang P, Havrdova E, Polman C, Rudick RA.

Abstract

IMPORTANCE: Walking impairment, a common clinical manifestation of multiple sclerosis (MS), is often measured in clinical practice and clinical trials using the Timed 25-Foot Walk (T25-FW).

OBJECTIVE: To evaluate the relationship between walking speed measured by the T25-FW and the ...
Read more : The clincial meaning of 'Walking Speed' | Views : 209 | Replies : 0


BREAKTHROUGH HOPE FOR MS TREATMENT AS SCIENTISTS DISCOVERS

http://www.dailymail.co.uk/health/artic ... eases.html
TEAM OF BRISTOL UNIVERSITY HAVE DESCRIBED THIER WORK AS AN BREAKTHROUGH CONDITIONS WHICH COULD BENEFIT INCLUDING MS AND TYPE1 DIABETES READ MORE FROM ATTACHED
REGARDS
seeva
Read more : BREAKTHROUGH HOPE FOR MS TREATMENT AS SCIENTISTS DISCOVERS | Views : 681 | Replies : 3


Which pattern is more characteristic of MS?

I got my blood test back and my b12 levels were completely normal.

Further indulging me into the possibility of MS. I have a question for all of you here. I get warm patches at random times on my extremities(and recently an eyelid) for 7 months now. I am wondering if any of you could give input on whether initial symptoms of oncoming MS is solely concentrated on a certain part/nerve, or would it be ...
Read more : Which pattern is more characteristic of MS? | Views : 265 | Replies : 1


General Question about being on Meds

I'm in a clinical study and on Copaxone - I'm newly diagnosed so don't know a lot about this disease and how it will affect my body or what to expect. I know it's different for everyone, but was hopeful I might gain some insight here. If you're on medication, what is the likelihood of being bound to a wheelchair in the first five years? Or maybe a better question is - does being on ...
Read more : General Question about being on Meds | Views : 331 | Replies : 3


 

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