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J Interferon Cytokine Res. 2016 Jun;36(6):347-57. doi: 10.1089/jir.2015.0177. Epub 2016 May 4.
Axon regeneration in the mature mammalian central nervous system (CNS) is extremely limited after injury. Consequently, functional deficits persist after spinal cord injury (SCI), traumatic brain injury, stroke, and related conditions that involve axonal disconnection. This situation differs from that in the mammalian peripheral nervous system (PNS), where long- distance axon regeneration and substantial ...
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