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MOGRIFY: WHAT´S THIS?

A predictive computational framework for direct reprogramming between human cell types.

Abstract

Transdifferentiation, the process of converting from one cell type to another without going through a pluripotent state, has great promise for regenerative medicine. The identification of key transcription factors for reprogramming is currently limited by the cost of exhaustive experimental testing of plausible sets of factors, an approach that is inefficient and unscalable. Here we present a predictive system (Mogrify) that combines gene ...
Read more : MOGRIFY: WHAT´S THIS? | Views : 304 | Replies : 2


Insights into white matter could help MS recovery

The cells that create myelin, a fatty material that insulates nerve fibres in the brain’s white matter, migrate into the developing brain by climbing and swinging on blood vessels, according to new research led by UC San Francisco scientists. ...Read more - http://www.ms-uk.org/MSnews
Read more : Insights into white matter could help MS recovery | Views : 271 | Replies : 1


Brain Health Resources - Trinity College Dublin Research

Researchers at Trinity College Dublin are developing online resources for people affected by Multiple Sclerosis. Everything they develop will be made freely available to the general public. They are looking for people living with MS, people who work with them, and their relatives, friends and loved ones to complete a survey in order to get their input and learn from their experiences. The survey can be accessed here: https://www.surveymonkey.com/r/MS_TCD ...
Read more : Brain Health Resources - Trinity College Dublin Research | Views : 254 | Replies : 2


Supplements and safety

I know a lot of us take supplements. I'm a proponent, but be careful - there is no regulation or testing in the USA, up to 60% of supplements are not what they say. Here is the Frontline story on this.

http://www.pbs.org/wgbh/frontline/film/ ... nd-safety/
Read more : Supplements and safety | Views : 231 | Replies : 0


MS biomarkers in the urine

Maybe an urine test is closer than we think:

Source:

http://pubs.acs.org/doi/abs/10.1021/acs ... me.5b01111

Abstract

Urine is a metabolite rich bio-fluid that reflects the body’s effort to maintain chemical and osmotic homeostasis. Clinical diagnosis routinely relies on urine samples since the collection process is easy and non-invasive.

Despite these advantages, urine is an under-investigated source of biomarkers for multiple sclerosis (MS).

Nuclear magnetic resonance spectroscopy (NMR) has become a common ...
Read more : MS biomarkers in the urine | Views : 268 | Replies : 0


How do I buy HSCT treatment?

I've been googling for an hour. I found the irf website with a list of hospitals in the world that perform the procedure. But do they do it to anyone, as in not in a clinical trial? Is there a place I can just pay for it. (Presumably not in the us because I don't have an endless source of funds.)

How do you go about getting it???
Read more : How do I buy HSCT treatment? | Views : 453 | Replies : 11


Newbie

Hello everyone,
My name is T and this is my 1st post. I don't know where to begin. I started having symptoms a few months ago that I couldn't just ignore anymore. I've always suffered with migraines and then I started experiencing pain and numbness in my hands a feet as well as my face. Then my knees started to ache. I went to the dr who scheduled me an MRI and results came back ...
Read more : Newbie | Views : 258 | Replies : 2


Canadian researchers from Sunnybrook and U of Toronto....

Regional reduction in cortical blood flow among cognitively impaired adults with relapsing-remitting multiple sclerosis patients.

http://www.ncbi.nlm.nih.gov/pubmed/26754799/
Read more : Canadian researchers from Sunnybrook and U of Toronto.... | Views : 297 | Replies : 1


Autoimmunity could be ‘dialled down’ study finds

A new study shows how dangerous autoimmune responses, seen in conditions such as lupus and multiple sclerosis, might be "dialed down" without compromising the immune system's ability to fight viruses and bacteria...Read more - http://www.ms-uk.org/MSnews
Read more : Autoimmunity could be ‘dialled down’ study finds | Views : 273 | Replies : 0


To do or not to?

Hello everyone! My physician has recommended Botox treatment for a temporary brow lift. I did an extensive research and found that it is the application of botox. This involves the injection of the botox into the areas between and at the outer corners of the eye brow. I have bee thinking about it for a while but also worried about its side effects. Drooping eyelids seem to be the side effect of botox injections. Anyone ...
Read more : To do or not to? | Views : 262 | Replies : 2


 

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