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Azathioprine versus beta interferons for RRMS

Azathioprine versus Beta Interferons for Relapsing-Remitting Multiple Sclerosis: A Multicentre Randomized Non-Inferiority Trial

Luca Massacesi, Irene Tramacere, Salvatore Amoroso, Mario A. Battaglia, Maria Donata Benedetti, Graziella Filippini, Loredana La Mantia, Anna Repice, Alessandra Solari, Gioacchino Tedeschi, Clara Milanese

Abstact

For almost three decades in many countries azathioprine has been used to treat relapsing-remitting multiple sclerosis. However its efficacy was usually considered marginal and following approval of β interferons for this indication it was no longer ...
Read more : Azathioprine versus beta interferons for RRMS | Views : 175 | Replies : 0


Limbspasm treatments for MS patients explored by 2 companies

Limb spasm treatments for MS patients explored by two companies

Upper limb spasticity and lower leg cramps and spasms, two conditions that affect patients with multiple sclerosis, are being treated in separate clinical trials with results from both showing positive benefits. Dysport (abobotulinumtoxinA), from Ipsen Biopharmaceuticals, Inc., and transient receptor potential (TRP) activators, from Flex Pharma, are proving to be effective in alleviating patients’ symptoms in novel ways..... Read More - http://www.ms-uk.org/mssymptomsresearch
Read more : Limbspasm treatments for MS patients explored by 2 companies | Views : 218 | Replies : 0


Intestinal parasites may help the immune system......

Intestinal parasites may help the immune system, researchers say

Almost two years ago, Julius Lukes sat down to a meal of raw fish riddled with tapeworm eggs. “I did not enjoy it,” he recalls. Happily, it took just a second or two: "You put it on your spoon and shovel it down".

Today, his intestines are home to three tapeworms with a total length of about 20 metres – all because Mr. Lukes, a senior ...
Read more : Intestinal parasites may help the immune system...... | Views : 186 | Replies : 0


DMT discontinuation review stirs MS research community

The U.S. Agency for Healthcare Research and Quality (AHRQ) recently released a draft review on the evidence on discontinuation of disease-modifying therapies. Shocked by the apparent lack of expertise in the first draft, MS researchers and advocacy groups sent in a wave of comments chastising the AHRQ for the perceived shoddiness of the report....... Read More - http://www.ms-uk.org/MSnews
Read more : DMT discontinuation review stirs MS research community | Views : 206 | Replies : 0


ISTRELI THERAPY MAY SLOW ON SLAUGHT OF M.S

http://www.israel21c.org/health/israeli ... sclerosis/
INRAVENOUS IMMUNOGLOBULIN SIGNIFICALLY LOWERED THE OCCURANCE OF A 2ND ATTACT ON M.S read more from the attached
regards
seeva
Read more : ISTRELI THERAPY MAY SLOW ON SLAUGHT OF M.S | Views : 254 | Replies : 0


Dissecting PN

Feeling that B12 is closely connected to my MS I connected with an ME/CFS forum where b12 is a HUGE topic of discussion. I met this Ozzie (PhD Bio-Chem) that has a new B12 transdermal oils co. He offered to review my genetic profile which I sent him. His review (highlights):

Hi PN,
I have done your snps and attach the file.
Green is good (-/-), red is bad (+/+).
Generally I don't take that ...
Read more : Dissecting PN | Views : 352 | Replies : 8


It looks like lemtrada/alemtuzumab got approved by the FDA

https://www.bostonglobe.com/business/20 ... story.html

what do you guys think about this?

It seems to be much more deleterious than tysabri if you are JC virus ab negative and more deleterious than b cell depleters like rituxan/ocrelizumab/ofatumumab

~25% of acquired autoimmune disease, infusion reactions, infections.

mouse doctor notes that some people with relapsing multiple sclerosis have long term remission after treatment with lemtrada, and there is even some data in SPMS. ...
Read more : It looks like lemtrada/alemtuzumab got approved by the FDA | Views : 172 | Replies : 0


19 and falling apart

Ever since puberty I've been the jumpy slightly uncoordinated kid. I played drums a ton and mostly attributed my lack of coordination to not practicing enough. I've had psychiatric problems that first appeared in middle school (anxiety, depression). I perceived some kind of cognitive developmental slowing, comparing myself to my peers. Mostly socially, but also in other areas.

My life has been a roller coaster and my issues have been a major strain on my ...
Read more : 19 and falling apart | Views : 460 | Replies : 15


Are MS attacks completely random?

I strongly believe there are reasons behind all my attacks, stress or excessive weight lifting and processed fast foods, and I need to know if others think their attacks have been randomly occurring for no reason, as I am not taking any meds and I will try to cut out the triggers and go at this naturally, your inputs are greatly appreciated
Read more : Are MS attacks completely random? | Views : 374 | Replies : 9


I am so confused, what is going on with me?

I will try to be breif, not sure if that is possible. I am not sure where to begin. I am so fatigued. numbness and tingling in arms and legs. blurred vision in only one eye off and on. bowel and bladder retention. tingling in left ear (weird, I know). pain in lower back that runs down left leg. vibrating sensation in right heal (this one is most resent). muscle tension in neck and upper ...
Read more : I am so confused, what is going on with me? | Views : 261 | Replies : 3


 

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