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Mouse model EAE is not a useful multiple sclerosis model...

Mouse model EAE is not a useful multiple sclerosis model - study

EAE is not a useful model for demyelinating disease

Peter O. Behanemail, Abhijit Chaudhuri

Abstract

Experimental allergic encephalomyelitis (EAE) is the commonest, readily induced, organspecific, autoimmune disorder of laboratory animals of its kind.

It is an artificial disorder brought about by the immunisation of susceptible animals with brain antigens in complete Freund׳s adjuvant (CFA).

Variations can be induced by altering the nature of ...
Read more : Mouse model EAE is not a useful multiple sclerosis model... | Views : 220 | Replies : 2


Grrr now my legs feel like concrete with pins and needles

So I had a scare of a relapse a few weeks ago but it was just a psuedo relapse. Everything got back to normal but as of thursday my legs have been like heavy weights but at the same time I have pins and needles from my stomach down to my toes. Two of my fingers on each hand also have pins and needles as well. I have had these symptoms before, other than the ...
Read more : Grrr now my legs feel like concrete with pins and needles | Views : 593 | Replies : 19


Intermittant fasting

Dr. Mosley tell us about how the intermittent fasting has reverse his diabetes. The purpose of fasting is to allow your body to repair itself. The body spends most of it's energy processing food. If your body is not processing the food you eat it has more energy to repair itself.

http://articles.mercola.com/sites/artic ... =624314713
Read more : Intermittant fasting | Views : 693 | Replies : 30


MS Body Type?

Odd study but the statistical significance they found was undeniable. Women with MS are tall and skinny, Men with MS are tall. I am 6'3" my parent were 5'8 and 5'2. I also have 11% bodyfat, but I been on a powerlifting regimen at the gym for a year.

http://www.hindawi.com/journals/isrn/2013/981070/

"...An intriguing finding of this study is that body height of patients with MS tends to be greater than ...
Read more : MS Body Type? | Views : 487 | Replies : 10


PPMS CSF induces inflammatory demyelination....

Progressive multiple sclerosis CSF induces inflammatory demyelination, axonal loss, and astrogliosis in mice

Cristofanilli M, Rosenthal H, Cymring B, Gratch D, Pagano B, Xie B, Sadiq SA.

Abstract

Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory demyelination and neurodegeneration throughout the CNS, which lead over time to a condition of irreversible functional decline known as progressive MS.

Currently, there are no satisfactory treatments for this condition because the mechanisms that underlie disease progression ...
Read more : PPMS CSF induces inflammatory demyelination.... | Views : 233 | Replies : 0


A-fib & MS

I have been battling a-fib for apx. 8 months. Rhythmol caused severe side effects & was discontinued. It made me so tired & lethargic, I was broken down emotionally. Now, I've been switched to metaprolol 25 mg & flecainide acetate 50 mg. Anyone has any experience with afib & MS?

Help.
Read more : A-fib & MS | Views : 347 | Replies : 6


NZ ms study

Some positive news from my neck of the woods. (New Zealand)

http://tvnz.co.nz/national-news/anti-ps ... dy-6057457
Read more : NZ ms study | Views : 900 | Replies : 12


Viral infections and autoimmunity hodge podge

An interesting collection of well written blog entries...
http://simmaronresearch.com/tag/epstein-barr-virus/
Read more : Viral infections and autoimmunity hodge podge | Views : 266 | Replies : 1


Anti-psychotic drugs to be used in multiple sclerosis study

New Zealand researchers have been given the green light to trial new treatments on multiple sclerosis patients using anti-psychotic drugs.

The researchers from Victoria University believe they may be able to reduce the symptoms of this debilitating disease using commonly prescribed drugs.

They say a lower dosage of Clozapine and Risperidone, which treat depression and schizophrenia, can be used to treat MS........ Read More - http://www.ms-uk.org/mssymptomsresearch
Read more : Anti-psychotic drugs to be used in multiple sclerosis study | Views : 263 | Replies : 0


MS Medication Selection

Hello all,

I am writing this on behalf of my mother (49y.o) who is "diagnosed" with RRMS since April 2014. How it all started: for about a week in February 2014, she had extreme ringing/roaring in the ears yet at the same time sensitivity to sound; lightheadedness and extreme vertigo; headaches; fatigue; brain fog. Her PCP ordered MRIs of the brain and spinal cord which revealed white matter lesions in the brain, warranting a visit ...
Read more : MS Medication Selection | Views : 786 | Replies : 24


 

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