This Is MS Multiple Sclerosis Community: Knowledge & Support

Been taking Aricept for cognitive impairments for almost 2 years now. It along with Namenda has seemed to help get rid of the brain fog and make me able to think. But someone else told me they stopped taking it because it accentuated these problems for them: sensitivity to light, sensitivity to noise, and tinnitus.

Is there a pharmacological basis for this? I'll readily admit I don't know much about things like that, but I ...

8) Hi, This is my 1st post. It was March '92, Senior yr. in College, & I got the Adult Chicken-Pox after babysitting 5 kids with them...I ASSUMED Iwas safe...you know how that goes! I haven't been well 1 SINGLE DAY SINCE! YIKES!

I have Lyme, HHV 1 & 6 and EBV...My MRI's show Demyelixation from Chronic Lyme Disease.

Any Thoughts?

Thanx A Million~Blue Eyes

Dear all,

The BBC ran the story below as part of the MS Awareness week. I've only had this disease 2 years (dxed two years ago - no symptoms before) - but this story is not a pleasant read. I'm just not sure how typical this story is - you see these terms 'late stage MS', 'end stage MS' but I'm not sure what this actually mean. They tell us that we can expect to ...

Diet and Supplements in MS: A Reasonable Approach

In some respects, the role of diet and dietary supplements in multiple sclerosis (MS) is controversial. The most conservative, mainstream approach purports that, because the evidence is inconclusive, dietary strategies should not play a significant part in MS treatment plans. At the other end of the spectrum, some have claimed that a particular diet or supplement can cure the disease.


“Both views are overstated and are not ...

This seems too early for the pipeline even...



Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis.

J Clin Invest. 2006 May 1;116(5):1317-1326.
Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ.
Discovery Research, Schering-Plough Biopharma, Palo Alto, California, USA. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Experimental Pathology and Pharmacology ...

Not specifically for MS but may help for those with RLS.

http://news.bbc.co.uk/1/hi/health/4969870.stm

Does anyone else have itching as a symptom? I had it for a short time last summer and now for the last two months, not just in my extremities but every where. I am currently taking Lyrica, Baclofen and Amitriptiline. I have phased out Neurontin and I am working on lowering my Lyrica dose. I was at 75mg twice a day, now 25mg twice a day. Not looking for free medical advice, so any help ...

Interesting US court decision that could end up with some/all patients being given access to drugs after phase I trials.



FDA Shock

In a stunning decision the DC Circuit Court of Appeals ruled yesterday that dying patients have a due process right to access drugs once they have been through FDA approved safety trials. The FDA's refusal to allow firms to sell and patients to buy these drugs "impinges upon an individual liberty deeply rooted ...

I like that they were able to remyelinate even after chronic demyelination in this study -- lucky mice.



Endogenous Cell Repair of Chronic Demyelination.

J Neuropathol Exp Neurol. 2006 Mar;65(3):245-256.
Armstrong RC, Le TQ, Flint NC, Vana AC, Zhou YX.
From the Department of Anatomy, Physiology, and Genetics (RCA, TQL, NCF, Y-XZ) and the Program in Neuroscience (RCA, NCF, ACV), Uniformed Services University of the Health Sciences, Bethesda, Maryland.

In multiple sclerosis lesions, remyelination typically ...

Uncoupleing Protein 2 is a new one on me. It looks interesting because it is involved in neuroprotection AND plays a role in insulin secretion.



Uncoupling Protein 2 Has Protective Function during Experimental Autoimmune Encephalomyelitis.

Am J Pathol. 2006 May;168(5):1570-1575.
Vogler S, Pahnke J, Rousset S, Ricquier D, Moch H, Miroux B, Ibrahim SM.
M.D. Institute of Immunology, University of Rostock, Schillingallee 70, 18055 Rostock, Germany; or to Bruno Miroux, Ph.D., BioTram, CNRS UPR9078, Faculte ...