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Demylination, but were afraid to ask?

I came accross this (oldish 1999) pdf while searching for something else. I have yet to read it, but flicking through it it appears to have a lot of explanations with diagrams of what is happening. I thought that someone else may find it interesting.
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1692682&blobtype=pdf found at http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1692682
Abstract
The pathophysiology of multiple sclerosis is reviewed, with emphasis on the axonal conduction properties underlying the production of symptoms, and the course of the disease. ...
Read more : Demylination, but were afraid to ask? | Views : 1172 | Replies : 2


Inosine

Hey,

Is there a best time to take Inosine?

With / without food?

Thanks
Read more : Inosine | Views : 1179 | Replies : 2


Life after pulse roids

In a few weeks I have a follow up with my neurologist. This will mark a year since I switched to him and he changed my meds to Avonex with pulse Solu-medrol every month. I feel that my current therapies are benefiting me significantly when compared to my disease activity prior to changing therapies . He mentioned previously that he would order the pulse roids for a year or two. In case he does not ...
Read more : Life after pulse roids | Views : 1081 | Replies : 1


My daughter

This post is for all of you who were so kind and supportive of both my daughter, Suzy, and me-- Jimmylegs, mormiles, lyndacarol, moonwolf, sh8un, wino, anecdote (Sarah), etc. I have an exciting update! (For those who were not so supportive, you will probably want to skip this post—no more fights, please!)

I have sent private emails to most of you, I believe, with the results of Suzy’s visit to her MS specialist this past ...
Read more : My daughter | Views : 7682 | Replies : 54


Could it be?

MacKintosh wrote:In different people, it manifests differently. Sometimes it gets into the brain and becomes MS, sometimes the joints and becomes rheumatoid arthritis, sometimes chronic fatigue syndrome, high blood pressure, etc.

If this is true then all the other research and drugs are just a mistake. All the people that are trying these drugs must really wonder if they are doing the right thing. For someone just starting out they have the neurologist telling them ...
Read more : Could it be? | Views : 1678 | Replies : 11


When might Campath be available?

Anybody have a theory re: when the drug will get out of trials, roughly?

Thanks to all.
Read more : When might Campath be available? | Views : 1490 | Replies : 6


Minocycline + interferon?

Anyone have any thoughts on the (theoretical) cumulative efficacy of combining minocycline and interferon? I found one study suggesting that the combination increases efficacy in EAE, but EAE is such a poor model of MS.

I'm particularly cautious given the recent study showing that combining statins with interferon significantly reduced the efficacy of both medications, with fairly poor results. On the other hand, I'd like to add minocycline, given that I think it probably offers ...
Read more : Minocycline + interferon? | Views : 1661 | Replies : 8


Nanotechnology and spinal cord repair

I found the link to this article on "ms news" submitted by art. I very much like the fact that it contains plenty of healthy caution, even though the subject matter could be very exciting indeed. Nanotechnology has already cropped up once or twice with regard to MS, and this approach of combining it with standard medicine seems to hold promise.
The subject of scar tissue is one which is very important to me since ...
Read more : Nanotechnology and spinal cord repair | Views : 954 | Replies : 0


Probiotic and regulatory T-cells

This isn't directly about MS, but discovering that certain probiotics can influence the number of regulatory T-cells is a new twist, especially when you consider how often digestive dysregulation crops up with regard to auto-immune disease:
http://www.eurekalert.org/pubnews.php

http://www.eurekalert.org/pubnews.php
Public release date: 21-May-2007


Contact: Adriane Hirsch-Klein
Adriane.Hirsch-Klein@mslpr.com
212-468-4122
Manning ...
Read more : Probiotic and regulatory T-cells | Views : 1354 | Replies : 1


Tracking a B-cell enzyme in living mice

Hello everyone,
We've talked before about where and how B cells mature from "naive" cells to "memory" cells, and how that process might be responsible for autoimmunity. During an infection, B cells migrate to the so-called Germinal centres where they divide rapidly. The enzyme AID causes random mutations at this point, presumably in the hope that this scattergun approach will stumble across the best defence. Unfortunately, any one of these random cells could have an ...
Read more : Tracking a B-cell enzyme in living mice | Views : 1085 | Replies : 0


 

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