This Is MS Multiple Sclerosis Community: Knowledge & Support

The UK MS Society is a poor cousin (financially) of the NMSS. However, this means that it sometimes funds some slightly different types of research.

I've never heard of amyl nitrite, but thought that CureorBust could add it to his (her) ever increasing list of drugs / supplements.

Ian

http://www.mssociety.org.uk/go.rm?id=19273:1

Hi all, just wanted to let people know about this stuff. I know I would of wanted to know about this earlier.

A few months ago I came accross the study Acordia are doing on a substance called 4-Aminopyridine (ie Fampradine, 4-AP). I followed some threads here, and found that a few people are actually getting it compounded, now. I thought it wouldnt be available

Anyway, I did more research, and eventually found out that ...

Not sure where to post this question, so I figure the general discussion might be best...

A bit of background info: I live in Canada, I have drug coverage through work and Tysabri is covered at the same level as the CRAB’s. Tysabri is available with a doctor’s prescription.

I’ve been diagnosed since 2005 and upon diagnosis, my neuro labeled me primary progressive. At a follow up visit in June 2006, he re-confirmed his PPMS ...

hi there, im new ..whas reading a few posts that mention BBB strengthening diets.

could someone point me in the direction of some details?
thanks
moonwolf uk

I am newly diagnosed (11/06). I haven't had my appointment with an MS Specialist yet (5/07), and wanted to know how some of the posters know they have RR or SP? Is there a test, is it tracking of symtoms/attacks? I was diagnosed about 2 weeks from my first symptom, so I am new to MS and am still trying to figure out the basics. My Neurologist assumed RR, but how do you know???

Hi - This is my first post.

I have been following this website for a month now. Those of you posting on this website ROCK! I love finding a community of people who seem so well educated, proactive and so open to finding an answer to improve their personnel or loved one's lot in life rather than waiting for it to flow off the pen of their doctors.

So - Thanks to everyone on this ...

Interesting answer about atrophy and axonal damage. Good to hear that research is very active in this area and work underway looking at neuro-protection. Sometimes when I read these sorts of answers, I'm still not clear if it is the myelin which is damaged first and then the axons, or the axons are damaged first resulting in secondary damage to the myelin!

http://www.msanswers.ca/QuestionView.aspx?L=2&QID=249

Ian

Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia.

Li Y, Chu N, Hu A, Gran B, Rostami A, Zhang GX.
Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA.

IL-12 has long been considered important in the pathogenesis of multiple sclerosis. However, evidence from recent studies strongly supports the critical role of IL-12-related proinflammatory cytokine IL-23, but not IL-12, in the development of experimental autoimmune encephalomyelitis (EAE), an animal model ...

U.S. survey boosts estimates of major neurological diseases
Updated: 11:10 a.m. ET Jan 30, 2007
WASHINGTON - Multiple sclerosis, Parkinson’s disease and other neurological diseases may be far more common than most people had believed, according to the latest estimates.
Nearly one out of 1,000 Americans has multiple sclerosis or MS and one out of 100 elderly Americans has Parkinson’s disease the survey found.
“Our estimate of MS prevalence is about 50 percent higher than ...

Here is a link to an article I found on, "MedPage Today",

http://www.medpagetoday.com/Neurology/M ... is/tb/4953

To be honest, I think they could have saved themselves the trouble and just written, "MS is quite complicated".

Ah well. I suppose even the most fruitless research is worth doing, because the answers we need might turn up in the most unexpected places,

Dom.