Bruce Trapp's work is viewed as cutting edge. It was his work in the late 1990s that showed that it was the damage to axons (nerve fibres) that caused disability rather than just de-myelination.
Nerve Fibres are Severed by Inflammation in MS Lesions, Leading to Permanent Disabilities
Bruce Trapp, PhD––Cleveland Clinic, Lerner Research Institute, Cleveland, Ohio
Multiple sclerosis (MS) is a chronic, disabling neurodegenerative disease. It strikes most often during early adulthood, and ...