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Long NYT Article - Fat Factors (microbe theory)

This was cover story of NY Times magazine a couple of weeks ago, it considers research into possible bacterial or viral component involvement in obesity. Its very good reading, and I thought it might be mildly relevant to those interested in similar theories regarding MS. I was also intrigued by discussion of gut microbes which, according to article, differ markedly between people; have both genetic and environmental influences; and could result in wide ranging health ...
Read more : Long NYT Article - Fat Factors (microbe theory) | Views : 969 | Replies : 2


Efficacy of mitoxantrone and intrathecal triamcinolone acetonide treatment in chronic progressive multiple sclerosis patients.Hellwig K, Schimrigk S, Lukas C, Hoffmann V, Brune N, Przuntek H, Muller T.
Department of Neurology, St. Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany.

ABSTRACT: Treatment approaches are rare for chronic progressive patients with multiple sclerosis (MS). Objective was to evaluate the clinical benefit of repeated intrathecal application of the sustained release steroid triamcinolone acetonide or the administration ...
Read more : Mitoxantrone/Triamcinolone | Views : 1134 | Replies : 4


I haven't got a clue what this research is saying but it keeps the researchers employed.

Relapses in Multiple Sclerosis and Correlation With Clinical and Biological Parameters: Presented at EFNS

10th Congress of the European Federation of Neurological Societies, Glasgow. 8th September 2006

The correlation of clinical and biological parameters with relapse in patients with multiple sclerosis (MS) demonstrates the prognostic importance of specific predictive relapse-related factors, according to a study presented here at ...
Read more : Relapses | Views : 914 | Replies : 1

Infections and relapses

Infection may raise MS relapse risk

Results of a study of adults with relapsing remitting multiple sclerosis point to a significant association between viral and bacterial infections and increased risk of relapse.

Investigators, in a report in the journal Neurology, note that published epidemiologic environmental observations point to infection as a possible causative factor or trigger in the onset of MS.

"Microorganisms induce strong immune responses specific for their own antigens, but microbial infections can ...
Read more : Infections and relapses | Views : 986 | Replies : 2


This is an old story so not sure why it's news again. Seems a safe and inexpensive treatment. Not sure why they can't test it on 50 male MS patients for a year and then, if positive results are seen, add it to the armoury!

Read more : Testosterone | Views : 1840 | Replies : 10


The makers of Sativex are seeking the treatment to be licenced in the UK and Europe. It has been licenced in Canada for some time. Has anyone from Canada had any experience of this treatment?

Read more : Sativex | Views : 1048 | Replies : 3


I'm noticing a lot of research abstracts mentioning p53 lately. I don't have a clue what it is, but if you look through old posts at ThisIsMS, you'll see some threads from OddDuck and BioDocFL talking a bit about it. I also just saw this abstract from last year from Vanderbilt and one of the oft-referenced researchers around here, Sriram.

Defective ATM-p53-mediated apoptotic pathway in multiple sclerosis.

Ann Neurol. 2005 Oct;58(4):577-84.
Deng X, Ljunggren-Rose A, ...
Read more : p53 | Views : 1281 | Replies : 3

More on EBV

We haven't had nearly enough posts on EBV in the last couple of weeks. I hope this article hasn't already been posted.

Epstein-Barr virus may increase risk of multiple sclerosis

Researchers have found that patients with multiple sclerosis carry a population of immune cells that overreact to Epstein-Barr virus.
The virus, which causes mononucleosis and may contribute to some cancers, has long been suspected to play a role in multiple sclerosis. However, the mechanism linking ...
Read more : More on EBV | Views : 1056 | Replies : 3

New animal model

A Beautiful New Model For MS
05 Sep 2006

Multiple sclerosis (MS) is a disease that affects the cells of the brain and spinal cord. MS can cause various symptoms, including depression, pain, and impaired mobility. Although it is clear that MS is caused by cells of the immune system inappropriately attacking the cells of the brain and spinal cord, much remains unknown about the disease. For example, what triggers the immune cells to attack; ...
Read more : New animal model | Views : 1658 | Replies : 4

TENS machine

Hello out there fellow MSers! Has anyone heard of or tried using a TENS machine to rebuild a muscle or muscle group? The central nervous system is affected, often the peripheral nerves are preserved. A Tens machine should function and help build muscle strength it seems. I am thinking of trying it. So, your experience would be greatly appreciated, thanks. Carolew :?
Read more : TENS machine | Views : 7894 | Replies : 19


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