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Still no evidence on the efficacy of immunomodulatory therap

Still no evidence on the efficacy of immunomodulatory therapy in reducing functional impairment in multiple sclerosis

* Vermeulen M.

Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Neurologie, Postbus 22.660, II00 DD Amsterdam..

Immunomodulatory therapy reduces the rate of relapse in multiple sclerosis (MS) by 30% in the first year of treatment; the effect in the second year is uncertain. Relapse is caused by the effects of inflammation ...
Read more : Still no evidence on the efficacy of immunomodulatory therap | Views : 1121 | Replies : 0

MS simulator machine

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Just maybe of interest to some...
Read more : MS simulator machine | Views : 1410 | Replies : 3

Th1 and Th2 responses: what are they?

This paper makes a few oft heard terms a little more understandable. I'm not certain of the exact date but I THINK it's from August 12, 2000.

Th1 and Th2 responses: what are they?

Abi Berger, science editor.


Cytokines are the hormonal messengers responsible for most of the biological effects in the immune system, such as cell mediated immunity and allergic type responses. Although they are numerous, cytokines can be functionally divided into ...
Read more : Th1 and Th2 responses: what are they? | Views : 3338 | Replies : 15

EBV / women / smoking / genes

This research tries to tie in various MS risk factors.

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Read more : EBV / women / smoking / genes | Views : 1131 | Replies : 1

Micro-RNA miR-155 and immune system regulation

Here's an interesting arctile on immune system regulation from the New York Times.


Studies Reveal an Immune System Regulator
By Nicholas Wade, April 27, 2007

Scientists working independently in Cambridge, England, and Cambridge, Mass., have discovered an unexpected regulatory network that affects the entire immune system.

The regulatory network may provide new clues to both the working of the body’s immune defenses and the generation of a class of cancers known as lymphomas, which ...
Read more : Micro-RNA miR-155 and immune system regulation | Views : 963 | Replies : 1

Interesting Tidbit I wasn't aware of

From 2002 Journal of Child Neurology

Gender prevalence in childhood multiple sclerosis and myasthenia gravis

Haliloglu, G.Show author details: Subscription required, Anlar, B.Show author details: Subscription required, Aysun, S.Show author details: Subscription required, Topcu, M.Show author details: Subscription required, Topaloglu, H.Show author details: Subscription required, Turanli, G.Show author details: Subscription required, Yalnizoglu, D.Show author details: Subscription required Correspondence address

Department of Pediatric Neurology, Hacettepe University, Ankara 06100, Turkey


Multiple sclerosis and myasthenia gravis are ...
Read more : Interesting Tidbit I wasn't aware of | Views : 970 | Replies : 0

Today mice, tomorrow humans?

I love stuff like this.

Mouse brain simulated on computer

BBC -- US researchers have simulated half a virtual mouse brain on a supercomputer.

The scientists ran a "cortical simulator" that was as big and as complex as half of a mouse brain on the BlueGene L supercomputer.

In other smaller simulations the researchers say they have seen characteristics of thought patterns observed in real mouse brains.

Now the team is tuning the simulation to ...
Read more : Today mice, tomorrow humans? | Views : 930 | Replies : 0

Change in MS ratio

The different rates of MS in men and women has always seemed to me to contain important clues about the origin of the disease. That ratio has changed dramatically over the years, and the difference has become even more pronounced, so maybe the clues might become a little bit more obvious:

Contact: Angela Babb <>
American Academy of Neurology <>
Over time, more women are developing MS than ...
Read more : Change in MS ratio | Views : 3387 | Replies : 22

Stem cells and scar tissue

My optimism about regenerative medicine has always been tempered by one thing: the presence of scar tissue at the site of any damage more than a few weeks or months old. Although his article is about transplanting retinal tissue, it also points out that stem cells can break through this barrier with the help of MMP-2.

Contact: Patti Jacobs <>
Schepens Eye Research Institute <>
Scientists identify key ...
Read more : Stem cells and scar tissue | Views : 1486 | Replies : 2


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