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 [ Total topics 6706 Go to page 1 ... 647, 648, 649, 650, 651, 652, 653 ... 671

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 Post subject: Allicin (garlic) & ALA as VLA-4 antagonists
PostPosted: Sat Nov 06, 2004 8:04 am 
Hey....here's something VERY interesting!

Looks like there are some additional "dietary" methods to possibly use, also, if an MSer is undergoing inflammation (remember, not all MSers experience inflammation - i.e. progressive MS), but this might be interesting to RRMSers particularly!

Deb

Immunology. 2004 Apr;111(4):391-9. Related Articles, Links


Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression.

Sela U, Ganor S, Hecht I, Brill A, ...

Read more : Allicin (garlic) & ALA as VLA-4 antagonists | Views : 1428 | Replies : 5

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 Post subject: iron and the brain
PostPosted: Fri Nov 05, 2004 5:45 pm 
Just thought this was interesting...


High-field magnetic resonance imaging of brain iron: birth of a biomarker?

Schenck JF, Zimmerman EA. - General Electric Global Research Center, Schenectady, New York, USA.

The brain has an unusually high concentration of iron, which is distributed in an unusual pattern unlike that in any other organ. The physiological role of this iron and the reasons for this pattern of distribution are not yet understood.

There is increasing evidence that ...

Read more : iron and the brain | Views : 1238 | Replies : 1

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 Post subject: Exercise and MS?
PostPosted: Tue Nov 02, 2004 4:01 am 
I am considering buying a treadmill for exercise purposes. My rationale being that if I regularly exercise walking the brain will form new axonal connections and my ability to walk will increase. It also has the added benefit of handrails for when things get a bit wobbly :lol:

However a motorised treadmill is a reasonably substantial investment. As such I wondered if anyone had any experience of ...

Read more : Exercise and MS? | Views : 1945 | Replies : 12

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 Post subject: Lies, damn lies and statistics
PostPosted: Mon Nov 01, 2004 3:16 pm 
Dear all,

Having this disease is a nightmare, but almost as bad (but not quite) is the quality of the information / data on this disease. Let me give a few examples:

- Many websites (e.g. of national societies) often say that by ten years after dx, 50% of RR ms sufferers move to Secondary Progressive (should this be regressive -progressive sounds like improvement?). On first reading, I assumed that the other 50% always stay ...

Read more : Lies, damn lies and statistics | Views : 2874 | Replies : 13

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 Post subject: Lesion load / auto-immune theory
PostPosted: Mon Nov 01, 2004 2:43 pm 
Dear all,

Many MS treatments refer to the effectiveness they have on reducing the 'lesion load'. In the case of Antegren, the speculation is that the effect might be much higher than current treatments. What does this term mean? Having less lesions (I assume) is a good thing and would result in less damage to the myelin and the underlying nerve cells. I assume that having less lesions would also allow the body to deal ...

Read more : Lesion load / auto-immune theory | Views : 1597 | Replies : 8

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 Post subject: ANYONE TAKE ACCUTANE?
PostPosted: Mon Nov 01, 2004 11:01 am 
I've noticed several lawyer commercials on tv proposing a link between MS and the acne drug Accutane. I took this drug for about two years. I was just wondering if anyone else had taken this drug or had heard of a possible link. I did a search and only found more law firms proposing a link between Accutane and Crohn's and lupus, but not MS. I am not sure if there is anything to the ...

Read more : ANYONE TAKE ACCUTANE? | Views : 2573 | Replies : 1

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 Post subject: MORE ON DESIPRAMINE (ceramide, bdnf, sodium density)
PostPosted: Sun Oct 31, 2004 8:06 am 
Hi, folks. Well, it has been a while since I’ve promoted the testing of desipramine for MS, and another thread this morning got me thinking I should check to see if anything new has come out lately, and sure enough. Here’s what I found.

We all are aware of how it is believed that ceramide plays a role in MS. The hypothesis is that you ideally would want to inhibit ceramide. Well, read this. We’ll ...

Read more : MORE ON DESIPRAMINE (ceramide, bdnf, sodium density) | Views : 2108 | Replies : 8

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 Post subject: Drug reps on Antegran
PostPosted: Wed Oct 27, 2004 8:46 am 
The following website has been reported as one used by various drug company sales reps. Read the various posts, ensuring that you go beyond the first page to the following pages of messages.

The one comment about Antegren losing effect after 18 months is quite astounding. You'll have to make your own conclusions.

Harry

http://www.cafepharma.com/ubbthreads/sh ... e=0#262902

Read more : Drug reps on Antegran | Views : 1922 | Replies : 8

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 Post subject: MS Historical, Regional and Suspected Causes.
PostPosted: Tue Oct 26, 2004 9:05 pm 
Very interesting reading with an overview on many different suspected causes and regional MS informaton, and historical references:

Areas covered:

Epidemiology
Disease Associations
Pathogenesis
Laboratory/Radiologic/Other Diagnostic Testing
Gross Appearance and Clinical Variants
Histopathological Features and Variants
Prognosis and Treatment

http://www.thedoctorsdoctor.com/disease ... _sclerosis.

Read more : MS Historical, Regional and Suspected Causes. | Views : 1866 | Replies : 2

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 Post subject: Brain Atrophy in RR and and SP Multiple Sclerosis
PostPosted: Tue Oct 26, 2004 9:03 pm 
http://radiology.rsnajnls.org/cgi/conte ... /214/3/665

Read more : Brain Atrophy in RR and and SP Multiple Sclerosis | Views : 1494 | Replies : 0

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 [ Total topics 6706 Go to page 1 ... 647, 648, 649, 650, 651, 652, 653 ... 671


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