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Genetic Predisposition

I know I brought this subject up about a year ago but there is no doubt that we have all learned a lot in the time since.

The assumption of genetic predisposition is one of the earliest and longest held assumptions in the history of modern MS research.

The assumption of genetic predisposition was/is based on incidence data showing that MS predominantly, at that time almost exclusively, affected light skinned caucasians, seemingly regardless of location ...
Read more : Genetic Predisposition | Views : 1855 | Replies : 5


PPMS Seminar from John Hopkins Group

Here's a link to something rare --- a seminar on PPMS.

http://www.msleaders.org/ms-leaders/cme ... essive.asp
Read more : PPMS Seminar from John Hopkins Group | Views : 1141 | Replies : 0


Worms (one for Lyon)

Lyon,

As the "worm man" you might be interested in the following. A different kind of worm, but British, so a superior worm than those you have promoted.

All the best

Ian

http://c.moreover.com/click/here.pl?j10 ... 9&w=464753
Read more : Worms (one for Lyon) | Views : 1441 | Replies : 2


More T-reg cells not necessarily better

Boosting the number of regulatory T cells sounds like a good idea because it calms down excessive immune activity directed against the body's own tissue. However, this research suggests that because T-reg cells also recognise foreign invaders like viruses and bacteria, boosting their numbers could calm down the response to these things as well, which would be unwelcome,


Public release date: 14-Sep-2007


Contact: Toni Baker ...
Read more : More T-reg cells not necessarily better | Views : 1020 | Replies : 0




Sweet sleep...

Dear MS community-

Please advise on how to help my husband, recently dx last March. He has difficulty staying asleep, due to painful spasms at night. The baclofen prescribed isn't effective.

It seems as though there's a vicious cycle going on, related to interrupted sleep cycles, leading to fatigue the next day. He's just plain zonked all the time. Amantadine and ginseng and caffeine get him thru the day, and he falls asleep easily at ...
Read more : Sweet sleep... | Views : 4682 | Replies : 22


CoreControl Cooling Glove

Newish cooling glove that uses the hand's natural radiators to cool the bodys inner core. Case study on use with people with MS.

http://www.avacore.com/pdfs/CoreControl ... tudies.pdf

My company in New Zealand is distributing these for athlete use so it was interesting to see this development. Unfortunately the gloves are very expensive $US 1,995. They are working on a consumer model for the future though.
Read more : CoreControl Cooling Glove | Views : 1404 | Replies : 2


Aspartame not bad for your health

So, Aspartame isn't neurotoxic after all. Be aware that the Burdock Group has close ties with the food industry, and the study was funded by Ajinomoto company inc, which is a Japanese giant producing amino acids, livestock foodstuffs, and dietary substances. I'm not questioning their independence, just advising that you consume this with a pinch of monosodium glutamate:

Public release date: 11-Sep-2007


Contact: Ellen Ternes ...
Read more : Aspartame not bad for your health | Views : 1505 | Replies : 4


Stupid Study

I read this study and it really pissed me off. Is it really saying that the majority of us are just crazy?!!! What criteria do they use to determine that these people presented with psychiatric manifestations? These kind of studies just perpetuate the feelings of the outside world that our problems are only in our minds.



This version was published on July 1, 2007
Multiple Sclerosis, Vol. 13, No. 6, 749-753 (2007)
DOI: 10.1177/1352458506075032
© ...
Read more : Stupid Study | Views : 3239 | Replies : 19


Possible genetic explanation for difference in incidence

Could be another piece of the puzzle...more study required...



Candidate gene analysis of SPARCL1 gene in patients with multiple sclerosis.

Neurosci Lett. 2007 Aug 17;
Scalabrini D, Fenoglio C, Scarpini E, De Riz M, Comi C, Venturelli E, Cortini F, Piola M, Villa C, Naldi P, Monaco F, Bresolin N, Galimberti D.
Department of Neurological Sciences, “Dino Ferrari” Center, University of Milan, IRCCS Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122 Milan, Italy.

Recently, proteomic ...
Read more : Possible genetic explanation for difference in incidence | Views : 1301 | Replies : 0


 

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