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If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

What would you ask an MS Specialist...

The day is finally approaching when I will have an appointment with an actual MS Specialist. I have my Medical records, my MRI films, my log of symptoms, and meds. I have many questions (most of which you all have answered either to me directly or to others on the forum - thanks...), but what should I be asking her.

This will be the first time someone other than the neurologist who diagnosed me will ...
Read more : What would you ask an MS Specialist... | Views : 1457 | Replies : 4

GA at 40mg better than 20

Is GA working for you? Ask your doc for more!!


Read more : GA at 40mg better than 20 | Views : 1015 | Replies : 2


Those three pesky letters turn up again...


Read more : BBB in EAE | Views : 938 | Replies : 0

connect the dots

I only understand about 20% of the words in the abstract (mostly "and", "in", "has" etc) but it's interesting to me anyway. It seems to tie together a number of different research areas in one study - specifically: pregnancy, endogenous retroviruses, chromosome 7q21-22, TNFalpha, interferon-gamma, interferon-beta and interleukin-6. I don't have a clue what it all means and it could be inconsequential, but so many different aspects of the disease mentioned in one abstract caught ...
Read more : connect the dots | Views : 1588 | Replies : 3

viruses again

This is an abstract from 2004 that I hadn't seen before. It suggests the possibility that when present simultaneously, endogenous retrovirus and herpesvirus have a synergistic effect, and not in a good way. It is interesting as the multiple viral trigger possibility has been studied a bit.

Simultaneous presence of endogenous retrovirus and herpes virus antigens has profound effect on cell-mediated immune responses: implications for multiple sclerosis.

AIDS Res Hum Retroviruses. 2004 Apr;20(4):415-23.
Brudek T, ...
Read more : viruses again | Views : 1901 | Replies : 9

Social Security Reform Update

Since Ar Mellor from the Accelerated Cure Project, Stuart Schlossman from Stu's Views and MS Related News, and a few other MS organizations have posted my Social Security Reform petition on their websites during the past few weeks, over 500 MS patients, physicians, members of disability advocacy organizations and other concerned citizens have rallied behind this important legislative reform effort. There's a long way to go to reach the 10,000 signature goal necessary to establish ...
Read more : Social Security Reform Update | Views : 1088 | Replies : 0

Rho and degeneration

The Rho protein might be part of the pathway which, during 'overexcitement' and excess Calcium levels, triggers neuronal cell death:


Read more : Rho and degeneration | Views : 1855 | Replies : 12

Stem Cell Info

More Stem Cell Info


Stem cell finding could help fight autoimmune disease
Posted by the Asbury Park Press on 03/19/07


In a finding that could help researchers better understand autoimmune disease,
scientists say a process called autophagy prompts dying embryonic stem cells to send out "eat me" and "come and get me" signals to ensure their elimination by healthy cells.

"Our findings also suggest that defects in autophagy might trigger autoimmune
diseases and, ...
Read more : Stem Cell Info | Views : 1275 | Replies : 0

Apoptosis and HHV6A

HHV6A, along with EBV is a strong condender for the role of viral villain in MS.

Apoptotic effects of Human Herpesvirus-6A on glia and neurons as potential triggers for central nervous system autoimmunity.

J Clin Virol. 2006 Dec;37 Suppl 1:S11-6.
Gardell JL, Dazin P, Islar J, Menge T, Genain CP, Lalive PH.
Department of Neurology, University of California, San Francisco

BACKGROUND: Human Herpesvirus type 6 (HHV-6A and/or HHV-6B) has been tentatively associated with multiple sclerosis ...
Read more : Apoptosis and HHV6A | Views : 1136 | Replies : 1

Clustering of autoimmune diseases

I find it dissapointing that researchers don't find clustering of these diseases as significant as I do, but this article shows that there is at least some consideration of the matter.

Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study.

Read more : Clustering of autoimmune diseases | Views : 1134 | Replies : 0


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