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If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

mast cells

Interesting potential...

Mast cells, T cells, and inhibition by luteolin: implications for the pathogenesis and treatment of multiple sclerosis.

Adv Exp Med Biol. 2007;601:423-30.
Theoharides TC, Kempuraj D, Iliopoulou BP.
Department of Pharmacology, Internal Medicine and Biochemistry, Immunology Program, Tufts University School of Medicine, Tufts-New England Medical Center, Boston, MA, USA.

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but ...
Read more : mast cells | Views : 1188 | Replies : 0

MS Diagnostics

Hi all,

Found this article re: a newly developed technique to test for a number of medical conditions, including MS. It is in the experimental stage, but sounds interesting. Below is the link and article.


Brain test could help make earlier diagnoses

A technique developed by a U scientist shows promise in detecting several neurological disorders for which there is no other single test.

By Maura Lerner, ...
Read more : MS Diagnostics | Views : 1266 | Replies : 0

How bacteria can get into the nervous system

Here's an interesting discovery about a possible way for bacteria to enter the CSF, which doesn't require the presence of blood brain barrier leakage:

Bacterial toxins and Multiple Sclerosis.

J Neurol Sci. 2007 Aug 17;

Authors: Gay F

The primary pathogenetic mechanism responsible for the distinctive demyelinating lesions in the Central Nervous System (CNS) in Multiple Sclerosis (MS), first described in remarkable detail by Charcot more than 170 years ago, remains one of the most ...
Read more : How bacteria can get into the nervous system | Views : 1838 | Replies : 0

Futures in Biotech

Here's a link to a bunch of very interesting podcasts / audio files wherein a number of experts are interviewed about their work in biotech, genomics, proteomics, brain science, systems biology, synthetic biology and even multiple sclerosis!
Read more : Futures in Biotech | Views : 1163 | Replies : 0

Immune and nervous system cells talk to each other

Signalling between cells is vital for correct functioning, but I didn't realise that the immune system and nervous system talked to each other quite so much:

Trends Immunol. 2007 Aug 3;
Franco R, Pacheco R, Lluis C, Ahern GP, O''connell PJ
Discuss | category: Immunology

Initially, the idea that neurotransmitters could serve as immunomodulators emerged with the discovery that their release and diffusion from nervous tissue could lead to signaling through lymphocyte cell-surface receptors and ...
Read more : Immune and nervous system cells talk to each other | Views : 1409 | Replies : 2

Switching meds...


I was on Rebif until last week and will be changing to a new medication next week. For those that have switched meds do you start out at low dosage again? Also do you feel the same initial pain as you did when you began your first treatment?

I'm worried that I was finally feel good on Rebif, but had to switch due to allergic reaction. Will I suffer in the begining again as ...
Read more : Switching meds... | Views : 1291 | Replies : 1

Growing neurons for experiments

I think we're all pretty disillusioned by the failure of animal models to provide an accurate experimental analogue of human MS. Hopefully this new development will provide a better tool for understanding the disease, as well as more relevant test results.

Main Category: Neurology / Neuroscience News
Article Date: 20 Aug 2007 - 13:00 PDT
Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem ...
Read more : Growing neurons for experiments | Views : 1495 | Replies : 7

Changing jobs - insurance concerns

I just received a job offer that i think i am going to accept. Can anyone walk me through the proper steps to ensure that i dont lapse my coverage? just a little nervous.
Read more : Changing jobs - insurance concerns | Views : 1757 | Replies : 1

The therapeutic plasticity of neural stem/precursor

This excerpt is off track from the general gist of the article but I thought it was interesting that they specifically enter into the inflammation healing/hurting effect Cure and I had discussed/debated earlier. Additionally, the talk a little about plasticity, which if my flavor of the month right now.

Journal of the Neurological Sciences xx (2007) xxx–xxx

The therapeutic plasticity of neural stem/precursor
cells in multiple sclerosis
Stefano Pluchino ⁎, Gianvito Martino
Neuroimmunology Unit-DIBIT ...
Read more : The therapeutic plasticity of neural stem/precursor | Views : 1211 | Replies : 0

Has anyone changed from Rebif to one of the ABC's?

Hi, I have been on Rebif for 2 months after being diagnosed with RRMS. I was told I am allergic to Rebif and need to try a new med. Can anyone tell me what differences they have found from Rebif to one of the other's?


Read more : Has anyone changed from Rebif to one of the ABC's? | Views : 1943 | Replies : 4


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