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Phase 1 trial completed

Vaccinex, Inc. has today announced the successful completion of a multicenter phase 1, randomized, double-blind, placebo-controlled, single ascending-dose safety and tolerability study in adult patients with multiple sclerosis.... Read More -
Read more : Phase 1 trial completed | Views : 272 | Replies : 1

MS drug 'may already be out there'

Depression and heart-disease drugs are to be tested in a trial to find treatments for multiple sclerosis from existing medicines, reports the BBC.

There are currently no treatments in the secondary progressive stage of the condition and doctors hope the necessary drugs are already out there, but have never been tested on MS.

More than 400 people will take part in the trial at University College London and the University of Edinburgh..... Read more - ...
Read more : MS drug 'may already be out there' | Views : 400 | Replies : 3

Clues to 'brain fog' in CFS & MS patients found.....

Clues to 'brain fog' in chronic fatigue & MS patients found in spinal fluid

People with chronic fatigue syndrome show a distinct pattern of immune system proteins in their spinal fluid, reports HealthDay - a finding that according to researchers could shed light on the "brain fog" that marks the condition.

The new study found that, compared with healthy people, those with chronic fatigue syndrome had lower levels of immune-system proteins called cytokines in the ...
Read more : Clues to 'brain fog' in CFS & MS patients found..... | Views : 291 | Replies : 0

solefenacin (Vesicare)

I'm sorry I don't have my resources at hand, but has anyone read the reports of the ingrediant in Vesicare being used to potentially regrow myelin? It was in Science Daily a month or so ago, I tweeted it out, so I'll look up the article.

I did a search on here to see if there'd been a discussion, but only found nocturia discussions, I'm sorry if I missed something!
Read more : solefenacin (Vesicare) | Views : 432 | Replies : 0

Participate in a study!

The Marginalization, Mental Health, and Empowerment Team at Teachers College, Columbia University is looking for individuals who would like to participate in a research study exploring the life experiences of individuals with Multiple Sclerosis. This survey should only take about 15-20 minutes.

After reading below, if you are willing and eligible, please click on the link below. Thank you in advance for your time and input! We would really appreciate it if you could pass ...
Read more : Participate in a study! | Views : 274 | Replies : 0

Not MS studied but possible aid to remyelination, amp b

Stimulation of monocytes, macrophages, and microglia by amphotericin B and macrophage colony-stimulating factor promotes remyelination. Jan 2015
Approaches to stimulate remyelination may lead to recovery from demyelinating injuries and protect axons. One such strategy is the activation of immune cells with clinically used medications, since a properly directed inflammatory response can have healing properties through mechanisms such as the provision of growth factors and the removal of cellular ...
Read more : Not MS studied but possible aid to remyelination, amp b | Views : 325 | Replies : 0

MS as Normal Pressure Hydrocephalus (NPH) new research

The dominant hypothesis in multiple sclerosis is that it is an autoimmune disease; however, there is considerable evidence that the immune attack on myelin may be secondary to a cytodegenerative event. Furthermore, the immune modulating therapies longest in clinical use, although modulating the frequency and severity of exacerbation, do not affect long-term progression towards disability. Clearly alternative perspectives on the etiology of multiple sclerosis are warranted. In this paper I outline the commonalities between idiopathic ...
Read more : MS as Normal Pressure Hydrocephalus (NPH) new research | Views : 612 | Replies : 8

ms and pneumonia

Hi there. My mum was diagnosed with MS around 15 years ago. She has progressed very fast over the years and is now bedridden and cannot move. This year so far she has been diagnosed with pneumonia twice, broken her hip, UTI and has spent a lot of time in hospital. I guess I'm wanting to know is this the beginning of the end? I feel so guilty but i just want it to be ...
Read more : ms and pneumonia | Views : 287 | Replies : 1

My bitter sweet story

My name is Shauna. I am 34 years old and from Pennsylvania. I do not have MS, however my best friend did. Her name was Leah. We were best friends since 3rd grade. We were always together. We went through life's ups and downs together. She was more of a sister than a friend. When she was just 16 years old, she was diagnosed with MS. I remember not knowing much about it but I ...
Read more : My bitter sweet story | Views : 447 | Replies : 7

MS as a disease of endothelial dysfunction

Lots of new research showing the connection between a dysfunction in the cellular lining of the 60,000 miles of blood vessels in the human body, called the endothelium, and multiple sclerosis. The endothelium is the largest secreting organ in our bodies, and when it doesn't work, diseases of neurodegeneration can occur, due to hypoperfusion (slowed cerebral blood flow.)

The aim of the study was to assess endothelial function in patients with MS and in ...
Read more : MS as a disease of endothelial dysfunction | Views : 386 | Replies : 0


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